BRAF and MEK inhibitors and their toxicities: a meta-analysis
M Garutti, M Bergnach, J Polesel, L Palmero… - Cancers, 2022 - mdpi.com
… and MEK inhibitors. Although many trials have compared BRAF and MEK inhibitor combination
… appropriate BRAF/MEK inhibitor combinations, we performed a meta-analysis of adverse …
… appropriate BRAF/MEK inhibitor combinations, we performed a meta-analysis of adverse …
Clinical outcomes of BRAF plus MEK inhibition in melanoma: A meta‐analysis and systematic review
Q Yu, J Xie, J Li, Y Lu, L Liao - Cancer Medicine, 2019 - Wiley Online Library
… that combination therapy of BRAF and MEK inhibition achieved better curative effect and …
meta-analysis to evaluate the efficacy and safety between BRAF inhibition plus MEK inhibition …
meta-analysis to evaluate the efficacy and safety between BRAF inhibition plus MEK inhibition …
[HTML][HTML] Efficacy and safety of BRAF inhibition alone versus combined BRAF and MEK inhibition in melanoma: a meta-analysis of randomized controlled trials
M Liu, X Yang, J Liu, B Zhao, W Cai, Y Li, D Hu - Oncotarget, 2017 - ncbi.nlm.nih.gov
… In conclusion, our current meta-analysis of five selected randomized controlled trials … MEK
inhibition had significant survival benefit over BRAF inhibition monotherapy. In addition, our …
inhibition had significant survival benefit over BRAF inhibition monotherapy. In addition, our …
[HTML][HTML] The potential of RAS/RAF/MEK/ERK (MAPK) signaling pathway inhibitors in ovarian cancer: A systematic review and meta-analysis
CSE Hendrikse, PMM Theelen, P Van Der Ploeg… - Gynecologic …, 2023 - Elsevier
… be partly due to the use of MEK inhibitors. In the subgroup analysis by type of MAPK inhibitor,
MEK inhibitors were the most effective MAPK inhibitor used as a single agent in ovarian …
MEK inhibitors were the most effective MAPK inhibitor used as a single agent in ovarian …
Risk of ophthalmic adverse effects in patients treated with MEK inhibitors: a systematic review and meta-analysis
C Alves, I Ribeiro, A Penedones, D Mendes… - Ophthalmic …, 2016 - karger.com
… meta-analysis aims to evaluate the risk of ophthalmic adverse effects associated with MEK
inhibitors… to evaluate the efficacy and safety of MEK inhibitors. Overall risk of ophthalmic ad…
inhibitors… to evaluate the efficacy and safety of MEK inhibitors. Overall risk of ophthalmic ad…
Cardiovascular adverse events associated with BRAF and MEK inhibitors: a systematic review and meta-analysis
RI Mincu, AA Mahabadi, L Michel, SM Mrotzek… - JAMA network …, 2019 - jamanetwork.com
… meta-analysis of 5 randomized clinical trials including 2317 patients, treatment with BRAF
and MEK inhibitors … compared with treatment with BRAF inhibitor monotherapy. The risks of …
and MEK inhibitors … compared with treatment with BRAF inhibitor monotherapy. The risks of …
Therapeutic efficacy and safety of combined BRAF and MEK inhibition in patients with malignant melanoma: a meta-analysis
P Chen, F Chen, B Zhou - OncoTargets and therapy, 2017 - Taylor & Francis
… Citation8 Hence, in this study, we have performed a meta-analysis to assess the therapeutic
… meta-analysis showed that the group treated with combination of BRAF and MEK inhibitors …
… meta-analysis showed that the group treated with combination of BRAF and MEK inhibitors …
The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis
P Chen, F Chen, B Zhou - Cutaneous and Ocular Toxicology, 2019 - Taylor & Francis
… and MEK inhibition are … meta-analysis was to appraise the differences in risk of selected
dermatological toxicities of combined BRAF and MEK inhibition versus the BRAF inhibition …
dermatological toxicities of combined BRAF and MEK inhibition versus the BRAF inhibition …
MEK inhibitor as single agent in low grade serous ovarian and peritoneal cancer: a systematic review and meta-analysis
L Musacchio, AA Valsecchi, V Salutari… - Cancer Treatment …, 2022 - Elsevier
… Phase II/III clinical trials tested different MEK inhibitors (MEKis) in this complex malignancy,
with heterogenous results. Purpose of this systematic review and meta-analysis is to define …
with heterogenous results. Purpose of this systematic review and meta-analysis is to define …
Risk of selected dermatological toxicities in cancer patients treated with MEK inhibitors: a comparative systematic review and meta-analysis
O Abdel-Rahman, H ElHalawani, H Ahmed - Future Oncology, 2015 - Taylor & Francis
… patients on the three MEK inhibitors (trametinib, selumetinib … were considered eligible for
the meta-analysis. The relative risk … : Our meta-analysis has demonstrated that MEK inhibitor-…
the meta-analysis. The relative risk … : Our meta-analysis has demonstrated that MEK inhibitor-…
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