… Conclusions and Relevance This meta-analysis shows that antibiotics as the initial treatment
for pediatric patients with uncomplicated appendicitis may be feasible and effective without …

… The complication and efficacy rates described in our meta-analyses of children differed from
data collated for adults, where antibiotic treatment for uncomplicated appendicitis seemed to …

… the optimal treatment of acute appendicitis (AA) in children. Even if appendectomy is the
most … in children, a large observational study performed in United Kingdom including 703 …

… strategy for patients with uncomplicated appendicitis, there is still … The aim of this systematic
review and meta-analysis was to … to uncomplicated appendicitis both in adults and children. …

… of appendectomy should be balanced against the risk of recurrent appendicitis in a child
who … of NOT for acute uncomplicated appendicitis (AUA) in children in the reported literature. …

… is between uncomplicated acute appendicitis (UAA) and complicated acute appendicitis (…
In the present study, an interval appendectomy was the treatment of choice for all patients …

… is an alternative to appendectomy. The purpose of this systematic review and meta-analysis …
of nonoperative treatment of nonperforated acute appendicitis in children in the literature. …

… Acute appendicitis is a common condition in the pediatric population. In patients with
uncomplicated appendicitis, laparoscopic appendectomy … as compared to open appendectomy …

Importance Appendectomy remains the standard of care for uncomplicated acute
appendicitis despite several randomized clinical trials pointing to the safety and efficacy of …

… This meta-analysis shows that appendectomy is more effective than antibiotic therapy for
definitive cure of acute uncomplicated appendicitis. However, since the incidence of …