… now shows obesity is better regarded as a disease of disordered … of obesity and the role of
genetics in the disease, focussing … the genetics of obesity and related metabolic disease in …

… of obesity. The goal of this book is to highlight the pathophysiolgy of obesity and associated
diseases. While a completely comprehensive discussion of the metabolic basis of obesity is …

… The current global obesity pandemic is the leading cause for the soaring rates of
metabolic diseases, especially diabetes, cardiovascular disease, hypertension, and non-alcoholic …

… innate and adaptive immunity in obesity-related metabolic disease, including the potential …
and is a key site of metabolic homeostasis and inflammation in obesity. Several studies have …

… heart disease (CHD).32, 33 In fact, it has been determined that patients who have the
metabolic syndrome and associated obesity have a 3-fold increase in the risk of CHD and stroke. …

… toward metabolic dysregulation with obesity. … metabolic disease despite massive obesity
(37). Impaired lipogenic/adipogenic capacity is associated with increased visceral fat in obese …

… and cardiovascular diseases. Adipose tissue (AT) dysfunction … Recently, increased autophagy
has been linked to obesity and AT … in the treatment of obesity-induced metabolic diseases. …

… of obesity on risk of metabolic diseases, especially type 2 diabetes. Another area of growing
… is the impact of obesity on complications or “fellow travelers” of the metabolic syndrome, …

… to elucidate the molecular basis for obesity and obesity-related metabolic diseases. These
… the treatment and prevention of obesity-related chronic diseases. Furthermore, the relatively …

… As a result, ER stress takes part in obesity, hepatic steatosis, and diabetes pathogenesis,
arising as a potential target to treat or even prevent metabolic diseases. The scientific …