… , and aromatics by microbes will involve an extensive manipulation of their metabolism.
This review discusses the importance of model strains by metabolic engineering as a powerful …

… Metabolic engineering strategies should take into account … an industrial strain through
metabolic engineering for pathway … and strain robustness under actual fermentation conditions. …

… using metabolic engineering approaches [5, 6]. This review focuses on metabolic engineering
… -based methods of classical strain breeding, synthetic pathway engineering for access to …

… , thus proposing adaptive evolutionary strain designs. Using … ) and compared its metabolic
engineering strategies for ethanol … Finally, we present metabolic engineering strategies for …

… developed, which allow for more complex metabolic engineering strategies to be identified.
Future incorporation of kinetic considerations will further improve strain design algorithms. …

… To address this problem, significant developments have been made towards co-cultivation
of more than one engineered microbial strains to distribute metabolic burden between the co-…

… achievement of metabolic engineering 115 . The native physiologies of microbial hosts have
a key … This has enabled the development of established microbial strains for the synthesis of …

… development of industrial microbial strains through systems metabolic engineering. We
illustrate their implementation using several case studies of microbial overproduction at large-…

… metabolic simulation, sophisticated enzyme engineering, … , and genomic engineering,
employed for developing microbial cell … metabolic engineering used to develop microbial strains …

… developing microbial strains by systems metabolic engineering, which can be considered
as metabolic engineering … Systems metabolic engineering allows successful development of …