Metabolic engineering of Pseudomonas putida for increased polyhydroxyalkanoate production from lignin

D Salvachúa, T Rydzak, R Auwae… - Microbial …, 2020 - Wiley Online Library
… In this study, we sought to engineer a base strain of P. putida to produce mclPHAs from
aromatic compounds and lignin using genomic integration of DNA throughout. We demonstrate …

Metabolic Engineering of Pseudomonas putida KT2440 to Produce Anthranilate from Glucose

J Kuepper, J Dickler, M Biggel, S Behnken… - Frontiers in …, 2015 - frontiersin.org
… and gives on overview over the metabolic engineering targets investigated in this study. …
could also lead to additional metabolic engineering targets to improve microbial oAB production. …

[HTML][HTML] Pseudomonas putida as a synthetic biology chassis and a metabolic engineering platform

E Martínez-García, V de Lorenzo - Current opinion in biotechnology, 2024 - Elsevier
… These few instances showcase the many metabolic engineering possibilities that P. putida
putida and its variants as a metabolic engineering and SynBio chassis regards its biosafety …

In-silico-driven metabolic engineering of Pseudomonas putida for enhanced production of poly-hydroxyalkanoates

I Poblete-Castro, D Binger, A Rodrigues, J Becker… - … engineering, 2013 - Elsevier
… systems metabolic engineering driven by in-silico modeling to tailor Pseudomonas putida
… as constraints, elementary flux mode analysis of a large-scale model of the metabolism of P. …

Metabolic engineering of Pseudomonas putida KT2440 for high-yield production of protocatechuic acid

J Li, BC Ye - Bioresource Technology, 2021 - Elsevier
… most encouraging metabolic engineering chasses for biological industry fermentative
production. Based on multilevel metabolic engineering, we developed a P. putida KT2440 strain to …

[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
… of metabolic engineering using the non-pathogenic soil bacterium Pseudomonas putida as
… The discussion is focused on what we perceive as the frontiers in the field of engineering P. …

Metabolic engineering of Pseudomonas putida for the simultaneous biodegradation of benzene, toluene, and p‐xylene mixture

JY Lee, JR Roh, HS Kim - Biotechnology and Bioengineering, 1994 - Wiley Online Library
… A recently developed metabolic engineering technique offers considerable promise as an
approach to the solution of complex metabolic barriers that prevent complete degradation of …

Metabolic Engineering of Pseudomonas putida KT2440 for the Production of para-Hydroxy Benzoic Acid

S Yu, MR Plan, G Winter, JO Krömer - Frontiers in bioengineering and …, 2016 - frontiersin.org
putida as a PHBA production host. Further metabolic engineering strategies can be applied
to enhance production, for example, balancing the precursors PEP and E4P or increasing …

Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440

GJ Bentley, N Narayanan, RK Jha, D Salvachúa… - … engineering, 2020 - Elsevier
Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst
… This lays the foundation for future P. putida metabolic engineering efforts to convert sugars …

Engineering of natural product biosynthesis in Pseudomonas putida

A Loeschcke, S Thies - Current opinion in biotechnology, 2020 - Elsevier
… This article presents the current state of engineering P. putida for the biosynthesis of …
and expression of biosynthetic genes, and smart metabolic engineering are key to success. …