Engineering the metabolic landscape of microorganisms for lignocellulosic conversion

JM Peña-Castro, KM Muñoz-Páez… - Microorganisms, 2023 - mdpi.com
… in metabolic engineering are essential to enhance the efficiency and yield of the conversion
… and cutting-edge metabolic engineering for lignocellulosic conversion is now, what new …

[HTML][HTML] Metabolic engineering for the utilization of carbohydrate portions of lignocellulosic biomass

J Kim, S Hwang, SM Lee - Metabolic Engineering, 2022 - Elsevier
metabolic engineering efforts devoted to the development of microorganisms that efficiently
convert the carbohydrate portion of lignocellulosic … -wide gene expression landscape. In a …

Death by a thousand cuts: the challenges and diverse landscape of lignocellulosic hydrolysate inhibitors

JS Piotrowski, Y Zhang, DM Bates, DH Keating… - Frontiers in …, 2014 - frontiersin.org
… Systems biology analyses and metabolic modeling combined … to overcome their drain on
conversion efficiency. We suggest … Prior to microbial conversion of lignocellulosic sugars into …

Diverse lignocellulosic feedstocks can achieve high field‐scale ethanol yields while providing flexibility for the biorefinery and landscape‐level environmental benefits

Y Zhang, LG Oates, J Serate, D Xie… - GCB …, 2018 - Wiley Online Library
… Depending on the region, there are a large number of potential lignocellulosic feedstocks …
One criticism of this approach is that feedstock diversity may lead to variability in conversion

Multiomic fermentation using chemically defined synthetic hydrolyzates revealed multiple effects of lignocellulose-derived inhibitors on cell physiology and xylose …

Y Zhang, JM Vera, D Xie, J Serate… - Frontiers in …, 2019 - frontiersin.org
conversion after glucose depletion was greatly impaired. We hypothesized that impaired xylose
conversion was caused by lignocellulose-… Our results suggest that xylose metabolism in Z…

… for the conversion of lignocellulosic biomass to hydrocarbon fuels and coproducts: 2018 biochemical design case update; biochemical deconstruction and conversion …

RE Davis, NJ Grundl, L Tao, MJ Biddy, EC Tan… - 2018 - osti.gov
… sugar conversion approach, reflecting modifications to underlying conversion operational …
The overarching process designs evaluated here convert biomass to diesel- and naphtha-…

Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose

JM Van Munster, P Daly, MJ Blythe, R Ibbett… - Biotechnology for …, 2020 - Springer
… We investigated the transcriptional landscape of A. niger to … the role of fatty acid metabolism
in hydrolase production via … for nitrate uptake and intracellular conversion to ammonium, …

Aromatic inhibitors derived from ammonia-pretreated lignocellulose hinder bacterial ethanologenesis by activating regulatory circuits controlling inhibitor efflux and …

DH Keating, Y Zhang, IM Ong, S McIlwain… - Frontiers in …, 2014 - frontiersin.org
metabolism are less well understood. We have developed an approach to elucidate the
metabolic and regulatory barriers to microbial conversion … to compare anaerobic metabolic and …

Lignocellulosic biomass transformations via greener oxidative pretreatment processes: access to energy and value-added chemicals

W Den, VK Sharma, M Lee, G Nadadur… - Frontiers in …, 2018 - frontiersin.org
Lignocellulosic biomass in the form of organic residues … As of today, relatively little bioenergy
comes from lignocellulosic … for the pretreatment of lignocellulosics with the explicit aim to …

Overcoming lignocellulose‐derived microbial inhibitors: advancing the Saccharomyces cerevisiae resistance toolbox

BA Brandt, T Jansen, JF Görgens… - Biofuels, Bioproducts …, 2019 - Wiley Online Library
… Efficient conversion of lignocellulosic biomass also requires … landscape of these strains.130,
131 The transcriptomes of the natural strains are also enriched in biological and metabolic