[HTML][HTML] Metabolic pathways as a novel landscape in pancreatic ductal adenocarcinoma
A Ali, U Chianese, C Papulino, A Toraldo, MEA Abakar… - Cancers, 2022 - mdpi.com
… is dependent on metabolic conditions, … , and pancreatic ductal adenocarcinoma is no
exception. In this review, we describe the metabolic features of pancreatic ductal adenocarcinoma …
exception. In this review, we describe the metabolic features of pancreatic ductal adenocarcinoma …
The complex landscape of pancreatic cancer metabolism
CM Sousa, AC Kimmelman - Carcinogenesis, 2014 - academic.oup.com
… the metabolic reprogramming seen in PDA. In this review, we discuss the metabolic landscape
… Roughly 90% of all pancreatic cancers are pancreatic ductal adenocarcinomas (PDA), an …
… Roughly 90% of all pancreatic cancers are pancreatic ductal adenocarcinomas (PDA), an …
[HTML][HTML] Exploring the metabolic landscape of pancreatic ductal adenocarcinoma cells using genome-scale metabolic modeling
… Pancreatic ductal adenocarcinoma (PDAC) is a major research focus because of its poor
therapy response and dismal prognosis. PDAC cells adapt their metabolism to … -scale metabolic …
therapy response and dismal prognosis. PDAC cells adapt their metabolism to … -scale metabolic …
[HTML][HTML] The roles of intratumour heterogeneity in the biology and treatment of pancreatic ductal adenocarcinoma
T Evan, VMY Wang, A Behrens - Oncogene, 2022 - nature.com
… changes in the chromatin landscape in metastatic cells. This study demonstrated that a
subset of metastatic lesions evolves a unique metabolic dependency on the oxidative pentose …
subset of metastatic lesions evolves a unique metabolic dependency on the oxidative pentose …
The proteomic landscape of pancreatic ductal adenocarcinoma liver metastases identifies molecular subtypes and associations with clinical response
… the metabolic and the ADEX/exocrine-like subtypes, which would not be attributed to acinar
cell contamination because this analysis used liver metastases. The metabolic association …
cell contamination because this analysis used liver metastases. The metabolic association …
Metabolic plasticity in heterogeneous pancreatic ductal adenocarcinoma
C Liang, Y Qin, B Zhang, S Ji, S Shi, W Xu, J Liu… - … et Biophysica Acta (BBA …, 2016 - Elsevier
… Pancreatic ductal adenocarcinoma (PDA) is one of the most … to be downstream events of
metabolic reprogramming. Because … Pancreatic ductal adenocarcinoma (PDA) is a devastating …
metabolic reprogramming. Because … Pancreatic ductal adenocarcinoma (PDA) is a devastating …
Features of metabolism associated molecular patterns in pancreatic ductal adenocarcinoma
J Chen, Y Wang, H Jiang - Cancer Gene Therapy, 2023 - nature.com
… Here, we systematically explored metabolic landscape and identified three metabolic
patterns associated with distinct outcomes. Features among heterogeneous metabolic patterns …
patterns associated with distinct outcomes. Features among heterogeneous metabolic patterns …
[HTML][HTML] … and chemoresistance in pancreatic ductal adenocarcinoma: Insights into targeting physicochemical barriers and metabolism as therapeutic approaches
TMA Carvalho, D Di Molfetta, MR Greco, T Koltai… - Cancers, 2021 - mdpi.com
… As a result of their metabolic reprogramming, cancer cells quickly adapt … cellular metabolic
landscape of the tumor niche [247]. The most-well known metabolic alteration in cancer cells …
landscape of the tumor niche [247]. The most-well known metabolic alteration in cancer cells …
[HTML][HTML] Molecular and metabolic subtypes correspondence for pancreatic ductal adenocarcinoma classification
P Espiau-Romera, S Courtois, B Parejo-Alonso… - Journal of Clinical …, 2020 - mdpi.com
… Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most aggressive solid
… [35] analysing the epigenetic landscape of PDAC samples identified super-enhancers and …
… [35] analysing the epigenetic landscape of PDAC samples identified super-enhancers and …
[HTML][HTML] Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma
LP Ferguson, J Gatchalian, ML McDermott… - Nature …, 2023 - nature.com
… Diverse genetic mouse models of pancreatic cancer and stage… lipid and fatty acid metabolism,
programs associated with … metabolic landscape in aggressive pancreatic cancer cells …
programs associated with … metabolic landscape in aggressive pancreatic cancer cells …
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