… based on liquid chromatography−mass spectrometry and 15 N uniform metabolic labeling
… of nitrogen-containing cell metabolites in metabolic profiling experiments. As a proof of …

… the metabolic profile is a necessary step to define the most proper strategy of drug optimization,
adjusting the metabolic … Anyway, it should be mentioned that metabolic profiles may differ …

… will consider only metabolic profiling and metabolomics in the … metabolomics and metabolic
profiling studies rely almost exclusively on 1 H NMR, GC–MS and liquid chromatography (LC…

… Metabolism has an essential role in biological systems. … as metabolic profiling, and it is
applied to define metabolic changes … Chromatography–mass spectrometry (MS) platforms are …

… s) across the chromatogram. This is a compromise in metabolic profiling of a wide diversity
of metabolite classes, of which not all classes are suited to the chromatographic phase and …

… UPLC/MS metabolite profiles The preparation of plasma samples for metabolic profiling
analysis by UPLC/MS involved a protein precipitation step to extract low-molecular-weight …

… We found that the metabolic profiles of PD, HC and NDC showed a tendency for separation
although partially overlapped (Fig. 5a). Six metabolites were identified changed in PD …

… Liquid chromatography/mass spectrometry (LC/MS) followed by multivariate statistical
analysis has been successfully applied to the plasma phospholipids metabolic profiling in type 2 …

… metabolic profiling analysis on human blood plasma by ultra-performance liquid
chromatography… protocol for gas chromatography (GC)/MS-based metabolic profiling of plasma …

… Here we outline the major benefits and strong-points of the field of holistic metabolic profiling
and also attempt to highlight weaknesses and challenges as well as suggested strategies …