New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages
… macrophages were solely glycolytic and that FAO and OXPHOS were characteristic of
anti-inflammatory macrophages… for M2 macrophages, and FAO has been found to occur also in M1 …
anti-inflammatory macrophages… for M2 macrophages, and FAO has been found to occur also in M1 …
The role of metabolic remodeling in macrophage polarization and its effect on skeletal muscle regeneration
F De Santa, L Vitiello, A Torcinaro… - Antioxidants & redox …, 2019 - liebertpub.com
… metabolic features, with a link between the metabolic pathways operating in MΦ and their
pro-/anti-inflammatory … will focus on the potentiality of manipulating metabolism to polarize MΦ. …
pro-/anti-inflammatory … will focus on the potentiality of manipulating metabolism to polarize MΦ. …
Itaconate links inhibition of succinate dehydrogenase with macrophage metabolic remodeling and regulation of inflammation
V Lampropoulou, A Sergushichev, M Bambouskova… - Cell metabolism, 2016 - cell.com
… -inflammatory IL-1β-HIF-1α axis. Itaconate is one of the most highly induced metabolites in
activated macrophages… Here, we show that itaconate modulates macrophage metabolism and …
activated macrophages… Here, we show that itaconate modulates macrophage metabolism and …
Nitric oxide modulates metabolic remodeling in inflammatory macrophages through TCA cycle regulation and itaconate accumulation
JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw… - Cell reports, 2019 - cell.com
… involved in glucose metabolism. Our findings reveal a fundamental role for iNOS-derived
NO in … metabolic remodeling and cytokine production in the pro-inflammatory macrophage. …
NO in … metabolic remodeling and cytokine production in the pro-inflammatory macrophage. …
Macrophages, meta‐inflammation, and immuno‐metabolism
… -metabolism explores the coregulation of energy metabolism … M1-skewed macrophages
are sustained in edematous, … macrophage phenotypes and impose distinct metabolic modes. …
are sustained in edematous, … macrophage phenotypes and impose distinct metabolic modes. …
Metabolic alterations in aging macrophages: ingredients for inflammaging?
AA Van Beek, J Van den Bossche… - Trends in …, 2019 - cell.com
… of inflammation. In this opinion piece, we summarize intrinsic alterations in macrophage …
We propose that alternatively activated macrophages (M2-like), which are yet pro-inflammatory, …
We propose that alternatively activated macrophages (M2-like), which are yet pro-inflammatory, …
Macrophages and the regulation of adipose tissue remodeling
G Martinez-Santibañez… - Annual review of …, 2014 - annualreviews.org
… macrophages contribute to the remodeling events in lean and obese states. Advancing our
understanding of the involvement of macrophages in adipose tissue remodeling … metabolism. …
understanding of the involvement of macrophages in adipose tissue remodeling … metabolism. …
Contribution of metabolic reprogramming to macrophage plasticity and function
KCEL Kasmi, KR Stenmark - Seminars in immunology, 2015 - Elsevier
… component of chronic inflammatory conditions. Recent work demonstrates that inflammatory
macrophage activation is tightly associated with metabolic reprogramming to aerobic …
macrophage activation is tightly associated with metabolic reprogramming to aerobic …
Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
… and trigger chronic low-grade inflammation, that promotes the … metabolism are currently
unknown. We therefore set out to study metabolic signatures of adipose tissue macrophages (…
unknown. We therefore set out to study metabolic signatures of adipose tissue macrophages (…
The metabolic signature of macrophage responses
… is to discuss recent findings linking macrophage functions and metabolism. … macrophage
activation by inflammatory stimuli. Indeed, now we know that pro-inflammatory macrophages …
activation by inflammatory stimuli. Indeed, now we know that pro-inflammatory macrophages …
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