Metabolic interactions in the tumor microenvironment

CA Lyssiotis, AC Kimmelman - Trends in cell biology, 2017 - cell.com
… cells in the tumor. The focus of this review is on the remodeling of the tumor microenvironment
that leads to pathophysiologic interactions that are influenced and shaped by metabolism. …

Metabolism shapes the tumor microenvironment

M Reina-Campos, J Moscat, M Diaz-Meco - Current opinion in cell biology, 2017 - Elsevier
metabolic regulation of tumor cells by the TME. The concepts to be discussed include the
existence of metabolic … CAFs) to tumor progression, and the regulation of tumor immunology by …

Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

E Yang, X Wang, Z Gong, M Yu, H Wu… - Signal transduction and …, 2020 - nature.com
… the TME, which suggested the involvement of exosome-mediated metabolic reprogramming
in the TME. The metabolic remodeling in stromal cells is influenced by the cancer cells and …

Metabolic remodeling as a way of adapting to tumor microenvironment (TME), a job of several holders

J Serpa - Tumor Microenvironment: The Main Driver of Metabolic …, 2020 - Springer
… develops and in addition, they must prosper in the microenvironment in the metastasized
organ. The metabolic remodeling requires not only the adjustment of metabolic pathways per …

[HTML][HTML] Influence of the tumor microenvironment on cancer cells metabolic reprogramming

V Gouirand, F Guillaumond, S Vasseur - Frontiers in oncology, 2018 - frontiersin.org
… associated metabolic remodeling is not restricted to malignant cells but is also found in tumor
13) suggesting that CAF-mediated metabolic remodeling may be a common trait of cancers. …

Metabolic exchanges within tumor microenvironment

P Chiarugi, P Cirri - Cancer letters, 2016 - Elsevier
… often requires a metabolic rewiring of cancer cells to meet changes in metabolic demand to
Tumor microenvironment highly contributes to metabolic rewiring of cancer cells, fostering …

Tumor microenvironment metabolism: a new checkpoint for anti-tumor immunity

NE Scharping, GM Delgoffe - Vaccines, 2016 - mdpi.com
tumor cells, T cells also operate at a metabolic disadvantage. The nutrient dearth of the tumor
microenvironment (TME) creates “metabolic … basics of tumor cell and T cell metabolism and …

[HTML][HTML] Tumor microenvironment and metabolic remodeling in gemcitabine‐based chemoresistance of pancreatic cancer

Z Gu, Y Du, X Zhao, C Wang - Cancer Letters, 2021 - Elsevier
… dense fibrous matrix in the tumor microenvironment (TME) is … Metabolic remodeling reduces
GEM transport and synthesis … ), immune cells, and metabolic remodeling in the induction of …

LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling

J Yang, F Liu, Y Wang, L Qu, A Lin - Cancer Letters, 2022 - Elsevier
… Given these facts, lncRNAs, as putative regulators of tumor initiation and progression, have
… in tumor metabolic reprogramming and tumor-immune microenvironment remodeling, and …

[PDF][PDF] Macrophages and metabolism in the tumor microenvironment

I Vitale, G Manic, LM Coussens, G Kroemer, L Galluzzi - Cell metabolism, 2019 - cell.com
Tumor-associated macrophages (TAMs) constitute a plastic and heterogeneous cell population
of the tumor microenvironment (TME… Here, we present the major metabolic circuitries that …