Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

SY Lunt, MG Vander Heiden - Annual review of cell and …, 2011 - annualreviews.org
glycolysis in providing carbons to generate biomass. We argue that the major function of
aerobic glycolysis is to maintain high levels of glycolytic … why increased glucose metabolism is …

Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited

A Vazquez, J Liu, Y Zhou, ZN Oltvai - BMC systems biology, 2010 - Springer
… cerevisiae cells also exhibit aerobic glycolysis, resulting in the excretion of the metabolic
byproducts, acetate and ethanol, respectively. More importantly, both for E. coli and for S. …

Aerobic glycolysis: a DeOxymoron of (neuro) biology

A Schurr, S Passarella - Metabolites, 2022 - mdpi.com
… pathway of energy metabolism, ie, glycolysis, was activated by … mitochondrial oxphos and
thus ‘aerobic glycolysis’. Although this … to resolve the metabolic mystery of ‘aerobic glycolysis’, …

Separation of metabolic supply and demand: aerobic glycolysis as a normal physiological response to fluctuating energetic demands in the membrane

T Epstein, L Xu, RJ Gillies, RA Gatenby - Cancer & metabolism, 2014 - Springer
… Our model, in contrast, proposes that aerobic glycolysis is not a disorder of metabolism but
simply … but upregulated activity of transporters required for cell division, growth, and migration. …

Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype

S Ganapathy-Kanniappan - Critical reviews in biochemistry and …, 2018 - Taylor & Francis
… Emerging data indicate that aerobic glycolysis in cancer also … requirements of certain
biosynthetic processes (eg nucleic acids). Next, the metabolic intermediates of aerobic glycolysis

Glycolysis

NS Chandel - Cold Spring Harbor Perspectives in …, 2021 - cshperspectives.cshlp.org
Glycolysis was the first metabolic pathway elucidated and is also referred to as the Embden–…
flux through glycolysis. This is sometimes referred to as anaerobic glycolysis or homolactic …

[HTML][HTML] Aerobic glycolysis is a metabolic requirement to maintain the M2-like polarization of tumor-associated macrophages

NM de-Brito, J Duncan-Moretti, HC da-Costa… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… about TAMs energetic metabolism and their metabolic requirements. … In this context, a better
characterization of TAM metabolic … TAM metabolic profile and define their main metabolic

Regional aerobic glycolysis in the human brain

SN Vaishnavi, AG Vlassenko… - Proceedings of the …, 2010 - National Acad Sciences
… measurements (Table 2), it is noteworthy that regional variations in CMRO 2 , the primary
measure of the brain's energy metabolism in this study, accounted for only 6% of the variance …

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

RJ DeBerardinis, A Mancuso… - Proceedings of the …, 2007 - National Acad Sciences
… to examine the metabolism of glioblastoma cells exhibiting aerobic glycolysis. In these cells,
the … Surprisingly, both these needs were met by a high rate of glutamine metabolism. First, …

Aerobic glycolysis: beyond proliferation

W Jones, K Bianchi - Frontiers in immunology, 2015 - frontiersin.org
… So far, we have described examples where aerobic glycolysis is not linked to proliferation.
However, proliferating cells normally switch their metabolism to aerobic glycolysis for all the …