… and lipid metabolism and metabolic crosstalk within the tumor microenvironment … pancreatic
tumor progression. In addition, the metabolic reprogramming involved in pancreatic cancer …

… Aberrant metabolism in pancreatic cancer poses a unique therapeutic strategy. We review
… clinical studies looking to exploit alterations in the metabolic circuitry of pancreatic cancer. …

… Taken together, this suggests that pancreatic tumor cells adapt to metabolically challenging
… Targeting PDAC-specific metabolic pathways thus represents a novel strategy to explore for …

… Recently, polyamine metabolism has been redefined as an anticancer strategy and may
be involved in antitumour immune responses [62, 63]. The RAS-RAF-MEK-ERK signalling …

… unorthodox strategies used by … metabolism, such as diabetes and obesity. Finally, we
discuss the translational potential of exploiting knowledge about pancreatic cancer metabolism for …

… dietary interventions targeting deregulated cancer metabolism has been considered for …
metabolism reprogramming in pancreatic cancer and the mechanisms of amino acid metabolism …

… metabolic systems in pancreatic cancer. Finally, we highlight the challenges and opportunities
for targeting lipid metabolism … therapy is emerging as an anticancer strategy and plays an …

… associated to reduced anticancer activity of both gemcitabine and paclitaxel, new therapeutic
strategies to target the K-Ras-dependent metabolic aberrations should therefore inhibit …

… As observed for several other cancers, pancreatic cancer cells … This supports the strategy
of treating pancreatic tumors with … two strategies is a promising avenue for pancreatic cancer …

… Pancreatic tumors are known to be heterogenic at the cellular level, with distinct metabolic
traits and … in order to lead to the development of more targeted therapeutic strategies. Patient …