Metabolomic profiling of the aqueous humor in patients with wet age-related macular degeneration using UHPLC–MS/MS
G Han, P Wei, M He, H Teng, Y Chu - Journal of proteome …, 2020 - ACS Publications
… Assessing metabolomic alterations in age-related macular degeneration (AMD) can provide
insights into its pathogenesis. We compared the metabolomic profiles of the aqueous humor …
insights into its pathogenesis. We compared the metabolomic profiles of the aqueous humor …
Plasma metabolomic profiles associated with three-year progression of age-related macular degeneration
… retinal function with dark adaptation (DA). Fasting plasma samples were also collected for
metabolomic profiling. … In conclusion, plasma metabolomic profiles are associated with clinical …
metabolomic profiling. … In conclusion, plasma metabolomic profiles are associated with clinical …
Metabolome-wide association study of neovascular age-related macular degeneration
… metabolic profiling can detect metabolic differences between NVAMD patients and controls
in a discovery cohort. The results of this work may lead to a better understanding of AMD …
in a discovery cohort. The results of this work may lead to a better understanding of AMD …
A plasma metabolomic profiling of exudative age-related macular degeneration showing carnosine and mitochondrial deficiencies
JM Chao de la Barca, B Rondet-Courbis… - Journal of Clinical …, 2020 - mdpi.com
… metabolomic profile of exudative age-related macular degeneration (AMD), we performed a
targeted metabolomics study … involved in the plasma metabolomic profile of exudative AMD, …
targeted metabolomics study … involved in the plasma metabolomic profile of exudative AMD, …
Metabolomics in age-related macular degeneration: a systematic review
XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
… revealed six new metabolites involved in the plasma metabolomic profile, suggesting
mitochondrial energetic impairments and carnosine deficiency might play a role in NVAMD. Han et …
mitochondrial energetic impairments and carnosine deficiency might play a role in NVAMD. Han et …
Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers
… of metabolomics for … metabolomic profiles of participants with neovascular AMD and those
of a control group. The current study aimed to characterize the plasma metabolomic profiles of …
of a control group. The current study aimed to characterize the plasma metabolomic profiles of …
Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts
… analysis of MS plasma metabolomic profiles from a large group of patients with AMD, and a
group of subjects older than 50 years with normal macula … the plasma metabolomic profiles of …
group of subjects older than 50 years with normal macula … the plasma metabolomic profiles of …
Metabolomics and age-related macular degeneration
… It should be noted that tears used in this study were obtained from patients with dry eye
syndrome [179] and so their metabolomic profiles and relative metabolite concentrations may …
syndrome [179] and so their metabolomic profiles and relative metabolite concentrations may …
Plasma metabolomics of intermediate and neovascular age-related macular degeneration patients
… In conclusion, this study demonstrates that the plasma metabolic profiles of IAMD patients
are more similar to controls than to NVAMD patients. These results suggest that when …
are more similar to controls than to NVAMD patients. These results suggest that when …
[HTML][HTML] Integrating metabolomics, genomics, and disease pathways in age-related macular degeneration: the EYE-RISK consortium
IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor… - Ophthalmology, 2020 - Elsevier
… In the current study, we performed the largest metabolomics analysis in AMD to date,
including 2307 AMD patients and 4294 control individuals from 5 cohorts. Using an NMR-based …
including 2307 AMD patients and 4294 control individuals from 5 cohorts. Using an NMR-based …
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