… In the present study, liver extract enhanced the ability of livermetastasis-derived human
colon cancer cells to invade a reconstituted basement membrane to a significantly greater …

… strategies of metastasis. We report here the development of such an ultra-… metastatic
model for human colon cancer. The model was established by: (1) SOI to the nude mouse colon …

… We have developed a model of regional lymph node metastases by injecting tumor cells
into the apical lymphoid follicle of the cecum in mice [73]. Dye distribution studies have shown …

… cancer progression to metastasis. Here, we report that metastatic colon cancer contains
clonally derived tumor … and the ability to differentiate into mature colon cells. Additionally, when …

… With this overall strategy, we have constructed a model of human colon cancer in nude mice
… that occur in human subjects. These include (i) local growth, (it) abdominal metastasis, (ifi) …

… tumor implantation on the liver. The results of this study demonstrate that liver metastases
from colon cancer … This study thus suggests that in colon cancer patients with liver metastasis, …

… -metastasis model of gastro-intestinal cancer, we screened human gastric cancer and colon
cancer … model of liver metastasis using the human colon cancer HCT-116 cell line in nude …

… model for metastatic colon cancer. The important combination of luciferase imaging allowing
prediction of metastasis … decrease likelihood of bowel obstruction before metastasis is key to …

… behavior of metastatic subpopulations of human colorectal cancers. We … colon cancer
model which developed and produced patient-like metastases could be useful for further cancer …

… cells rather than the carcinoma cells within human colon cancer metastases (our unpublished
observations). While TGFa is secreted by a variety of human colon cancer lines, this …