Treatment landscape of metastatic pancreatic cancer

S De Dosso, AR Siebenhüner, T Winder, A Meisel… - Cancer treatment …, 2021 - Elsevier
… harbor metastases at diagnosis and predicted the number and size distribution of metastases
as … pattern of pancreatic cancer metastasis is critical for designing effective interventions. …

Current and emerging therapies in metastatic pancreatic cancer

GA Manji, KP Olive, YM Saenger, P Oberstein - Clinical Cancer Research, 2017 - AACR
… In this review, we discuss the current treatment options for metastatic pancreatic cancer
and highlight current ongoing clinical trials, which aim to target the stroma and the immune …

The pathology and genetics of metastatic pancreatic cancer

S Yachida… - Archives of pathology & …, 2009 - meridian.allenpress.com
Metastatic disease is the most critical determinant of resectability of pancreatic cancer and
… Thus, a better understanding of metastatic pancreatic cancer will afford new opportunities …

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

T Conroy, F Desseigne, M Ychou… - New England journal …, 2011 - Mass Medical Soc
… FOLFIRINOX is an option for the treatment of patients with metastatic pancreatic cancer
and good performance status. (Funded by the French government and others; ClinicalTrials.gov …

Metastatic pancreatic cancer: American Society of Clinical Oncology clinical practice guideline

DPS Sohal, PB Mangu, AA Khorana… - Journal of Clinical …, 2016 - ascopubs.org
… with metastatic pancreatic cancer? What is the appropriate therapy for patients with metastatic
pancreatic cancer … with prior regimens for metastatic pancreatic cancer? When should the …

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

PJ Campbell, S Yachida, LJ Mudie, PJ Stephens… - Nature, 2010 - nature.com
… rearrangements in 13 patients with pancreatic cancer and explore clonal relationships
among metastases. We find that pancreatic cancer acquires rearrangements indicative of …

Pancreatic cancer

T Kamisawa, LD Wood, T Itoi, K Takaori - The Lancet, 2016 - thelancet.com
… Tumour biology of pancreatic cancer contributes to early recurrence and metastasis, and …
shown that about 90% of cases of pancreatic cancer are complicated by distant metastasis. …

Metastatic pancreatic cancer: ASCO guideline update

DPS Sohal, EB Kennedy, P Cinar, T Conroy… - Journal of Clinical …, 2020 - ascopubs.org
… The aim of this work was to provide an update to the ASCO guideline on metastatic
pancreatic cancer pertaining to recommendations for therapy options after first-line treatment. …

Metastatic pancreatic cancer: ASCO clinical practice guideline update

DPS Sohal, EB Kennedy, A Khorana… - Journal of Clinical …, 2018 - ascopubs.org
Purpose In 2016, ASCO published a guideline to assist in clinical decision making in metastatic
pancreatic cancer for initial assessment after diagnosis, first- and second-line treatment …

Systemic therapy for metastatic pancreatic cancer

TJ Ettrich, T Seufferlein - Current treatment options in oncology, 2021 - Springer
… at an advanced or even metastatic state. Surgery is only … of metastasis is not appropriate
in pancreatic cancer outside of a clinical trial even in the case of isolated liver metastasis since …