Circulating tumor cell and circulating tumor DNA assays reveal complementary information for patients with metastatic urothelial cancer
… ” blood tests are emerging for urothelial cancer aimed at … such tests provide complementary
information: circulating tumor … of a person’s cancer, whereas circulating tumor DNA may be …
information: circulating tumor … of a person’s cancer, whereas circulating tumor DNA may be …
Circulating and urinary tumour DNA in urothelial carcinoma—Upper tract, lower tract and metastatic disease
… urothelial carcinoma, liquid biopsies such as plasma circulating tumour DNA (ctDNA) and
urinary tumour DNA … multiplex urinary methylation assay named urine tumour DNA methylation …
urinary tumour DNA … multiplex urinary methylation assay named urine tumour DNA methylation …
Circulating tumor DNA reveals clinically actionable somatic genome of metastatic bladder cancer
G Vandekerkhove, T Todenhöfer, M Annala… - Clinical cancer …, 2017 - AACR
… of circulating tumor DNA (ctDNA) from the plasma of patients with metastatic bladder cancer
captures the … Control DNA for testing the targeted sequencing panel was extracted from …
captures the … Control DNA for testing the targeted sequencing panel was extracted from …
Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA
… Although to the best of our knowledge no targeted therapies currently are approved for the
treatment of mUC, ctDNA NGS tests can be used for multiple GAs that have matched targeted …
treatment of mUC, ctDNA NGS tests can be used for multiple GAs that have matched targeted …
[HTML][HTML] Next-generation sequencing (NGS) of cell-free circulating tumor DNA and tumor tissue in patients with advanced urothelial cancer: a pilot assessment of …
… Our results support the need for further assessment of the clinical utility of NGS testing in
informing treatment decisions for these patients, especially in the current era with multiple …
informing treatment decisions for these patients, especially in the current era with multiple …
Emerging roles of urine-based tumor DNA analysis in bladder cancer management
AA Chaudhuri, B Pellini, N Pejovic… - JCO Precision …, 2020 - ascopubs.org
… biopsy assays to urinary DNA to evaluate urothelial cancer noninvasively (assays summarized
in … UroSEEK has been the most broadly tested and consists of 3 tests, all applied to urine …
in … UroSEEK has been the most broadly tested and consists of 3 tests, all applied to urine …
Novel use of circulating tumor DNA to identify muscle-invasive and non–organ-confined upper tract urothelial carcinoma
HL Huelster, B Gould, EA Schiftan, L Camperlengo… - European urology, 2024 - Elsevier
… Mantel-Cox log-rank testing assessed the association between … Here, we show that DNA
from upper tract urothelial tumors … tumor DNA can be used to predict that upper tract urothelial …
from upper tract urothelial tumors … tumor DNA can be used to predict that upper tract urothelial …
… detection of metastatic relapse and monitoring of therapeutic efficacy by ultra-deep sequencing of plasma cell-free DNA in patients with urothelial bladder carcinoma
E Christensen, K Birkenkamp-Demtröder… - Journal of Clinical …, 2019 - ascopubs.org
… , were used to assess circulating tumor DNA (ctDNA) by ultra-… found ctDNA testing in patients
with bladder cancer who … of treatment response, and early detection of metastatic relapse. …
with bladder cancer who … of treatment response, and early detection of metastatic relapse. …
Circulating tumor DNA analysis in advanced urothelial carcinoma: insights from biological analysis and extended clinical follow-up
SV Lindskrog, K Birkenkamp-Demtröder… - Clinical Cancer …, 2023 - AACR
… Personalized, tumor-informed ctDNA assays (Signatera) were designed as previously …
derived from WES of tumor tissue were selected for multiplex PCR (mPCR) testing. mPCR primers …
derived from WES of tumor tissue were selected for multiplex PCR (mPCR) testing. mPCR primers …
Tumor-agnostic circulating tumor DNA testing for monitoring muscle-invasive bladder cancer
R Carrasco, M Ingelmo-Torres, R Trullas… - International Journal of …, 2023 - mdpi.com
… monitoring cancer patients. Here, we aimed to ascertain whether tumor-agnostic ctDNA testing
… and therapeutic response in muscle-invasive bladder cancer (MIBC) patients after radical …
… and therapeutic response in muscle-invasive bladder cancer (MIBC) patients after radical …
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