… To best identify the specific MGMT promoter region most predictive of gene silencing and …
the methylation status of all 97 CpG sites in the MGMT promoter in tumor samples from 70 GBM …

… In this study, the most suitable sample specimen to be used for MGMT methylation analysis
… that MGMT promoter methylation status is highly concordant also between tumor tissues and …

… MGMT testing should be made mandatory, and whether temozolomide should be withheld
from patients with tumors that lack MGMT promoter methylation… to four biopsy specimens from …

… MGMT methylation assay using pyrosequencing on glioblastoma. We quantified promoter
methylation of MGMT … pyrosequencing, we reviewed 50 consecutive GBM biopsy specimens in …

… MGMT promoter was unmethylated (21.7 vs. 12.7 months) [5]. This study demonstrated the
potential importance of MGMT promoter methylation … consider MGMT promoter methylation as …

… A variety of different methods are being used to assess MGMT promoter methylation in
clinical samples, which may give rise to inter-laboratory variations in test results. …

… both MGMT promoter methylation status and MGMT expression data were dependant on
the site of sample collection within a glioblastoma and if data were pre-operatively predictable. …

… are designated Mer+ (to designate competence for repair of DNA methylation damage). …
We compared the methylation patterns of tumor specimens and normal colorectal mucosa. In …

… for specimens without MGMT promoter methylation status that had negative … MGMT promoter
methylated tumors with high MGMT protein expression as well as unmethylated tumors with …

… patients with MGMT promoter methylated tumors derived most … patients with MGMT promoter
methylated tumors derive benefit … The major strengths of this study include the large sample …