miR-145 and miR-143 regulate odontoblast differentiation through targeting Klf4 and Osx genes in a feedback loop

H Liu, H Lin, L Zhang, Q Sun, G Yuan, L Zhang… - Journal of Biological …, 2013 - ASBMB
Dentin tissue is derived from mesenchymal cells induced into the odontoblast lineage. The
differentiation of odontoblasts is a complex process regulated by several transcriptional
factor signaling transduction pathways. However, post-translational regulation of these
factors during dentinogenesis remains unclear. To further explore the mechanisms, we
investigated the role of microRNA (miRNA) during odontoblast differentiation. We profiled
the miRNA expression pattern during mouse odontoblast differentiation using a microarray …
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