MicroRNAs (miRNAs) are short, non-coding RNAs that regulate the expression of mRNA
targets and play a part in the post-transcriptional silencing. To date, the prominent roles of
miRNAs in stem cells have been investigated in a wide range of biological processes,
including self-renewal, differentiation and proliferation. In this commentary, we first
demonstrate the causes and mechanisms of somatic stem cell aging in a new aspect of
miRNAs. The functions of stem cells decline with age in diverse tissues due to cellular …