The space dimension at the micro level: mass spectrometry imaging of drugs in tissues

E Davoli, M Zucchetti, C Matteo… - Mass spectrometry …, 2021 - Wiley Online Library
… environmental toxicology, where levels of pollutants are … levels are intratissue at the
microenvironment level (Davoli, 2017). Creating molecular images with mass spectrometry imaging (…

Mass spectrometry imaging and profiling of single cells

EJ Lanni, SS Rubakhin, JV Sweedler - Journal of proteomics, 2012 - Elsevier
… /ionization mass spectrometry (MALDI MS)–are most often used in micro-bioanalytical …
spectrometry imaging (MSI) mode can routinely reach spatial resolutions at the submicron level; …

Imaging mass spectrometry

LA McDonnell, RMA Heeren - Mass spectrometry reviews, 2007 - Wiley Online Library
imaging mass spectrometry, Section VIII of this review details the multiple steps necessary to
obtain mass spectrometric images … more practical levels and allowed different imaging data …

Characterisation of a micro-plasma for ambient mass spectrometry imaging

A Bowfield, J Bunch, TL Salter, RT Steven, IS Gilmore… - Analyst, 2014 - pubs.rsc.org
… resolution of a non-thermal micro-plasma device. Not only do these investigations aid in
establishing the desired conditions in which mass spectrometry imaging (MSI) can be achieved …

Micro‐lensed fiber laser desorption mass spectrometry imaging reveals subcellular distribution of drugs within single cells

Y Meng, X Cheng, T Wang, W Hang, X Li… - Angewandte …, 2020 - Wiley Online Library
… mass spectrometry imaging method by introducing the sampling laser with a single-mode
micro-… at the organelle level, which is difficult to achieve with existing techniques. We used this …

Emerging technologies in mass spectrometry imaging

JH Jungmann, RMA Heeren - Journal of proteomics, 2012 - Elsevier
… This poses a challenge to conventional secondary-electron MS detectors (like micro-channel
plates (MCP) or photo-multiplier tubes) for which the mass response levels off for larger …

Mass spectrometric imaging of small molecules

A Svatoš - Trends in biotechnology, 2010 - cell.com
… Because established imaging methods are not able to … in one such method, mass
spectrometric imaging (MSI). Lipids, … well as sample preparation, imaging software, and medical …

Next Generation of Mass Spectrometry Imaging: from Micrometer to Subcellular Resolution

L Xing, CL Zhao, HZ Mou, JB Pan, B Kang… - … & Biomedical Imaging, 2023 - ACS Publications
… Due to the introduction of the near-field optical system, mass spectrometry imaging can
brake the diffraction limit and easily achieve submicrometer level imaging resolution, …

Mass spectrometry imaging with high resolution in mass and space

A Römpp, B Spengler - Histochemistry and cell biology, 2013 - Springer
… techniques, mass spectrometry imaging can differentiate … We have recently introduced the
first mass spectrometry imaging … new insights about molecular processes on the cellular level. …

[HTML][HTML] Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson, L Li - Analytical chemistry, 2018 - ncbi.nlm.nih.gov
… the image into its constituent regions at hierarchical levels. This … micro-dissection instrument
(capable of both bright-field and … imaging) with an electrospray ionization mass spectrometer