… of techniques for studying the functions of genes encoding miRNAs, several lines of evidence
indicate that miRNAs play an important role in malignant transformation of human cells. …

… MicroRNAs (miRNAs) are a family of small non-coding RNAs … In cancer cells, miRNAs have
been found to be heavily … region in B-cell chronic lymphocytic leukemia cells. They found this …

… in human primary neural (HNG) cells (a co-culture of neurons and astroglia). Specific miRNA
up-regulation was monitored using miRNA arrays, Northern micro-… cells of the human brain. …

… In human cells, after transfection of miRNAs by vectors or miRNA precursors, and subsequent
activation of RISC activity, the core component of RISC, together with the triggering miRNA …

… RNAs termed micro RNAs (miRNAs). Previously, we have demonstrated that miR-30, a
22-nucleotide human … Here, we show that a second human miRNA, termed miR-21, can also be …

… cells in mammals (39). The fact that many micro RNAs’ sequences are conserved among
distantly related organisms indicates that miRNAs are involved in basic cellular processes (40). …

… receptor positive ductal cell line MCF7, human fat and blood [38, 39]. Strikingly, we can model
the profile of a human cancer by simply combining tumor cell line and human fat profiles at …

… within pathways that control cell cycle checkpoints. … microRNA activity may be cell cycle
dependent, and we outline how the coordinate regulation of microRNA targets may influence cell …

… Animal cells have recently been shown to express a range of ∼22 nucleotide noncoding
RNAs termed micro RNAs (miRNAs). Here, we show that the human mir-30 miRNA can be …

… MicroRNAs are able to regulate various biological processes such as cell growth (including
stem cells… biogenesis and disorders in miRNA genes related to malignization of human cells. …