Microbial genome analysis: the COG approach

MY Galperin, DM Kristensen… - Briefings in …, 2019 - academic.oup.com
… neighborhoods, in many cases allowing prediction of novel functional systems; (iv) analysis
… and drawbacks in microbial genome analysis. comparative genomics, genome annotation, …

Using comparative genome analysis to identify problems in annotated microbial genomes

MS Poptsova, JP Gogarten - Microbiology, 2010 - microbiologyresearch.org
… Here we discuss and demonstrate how the methods of comparative genome analysis can
… Since old errors may propagate to the newly sequenced genomes, we emphasize that the …

Microbial genome analysis: insights into virulence, host adaptation and evolution

BW Wren - Nature Reviews Genetics, 2000 - nature.com
Genome analysis of microbial pathogens has provided unique insights into their virulence,
host adaptation and evolution. Common themes have emerged, including lateral gene …

Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer

JC Arthur, RZ Gharaibeh, M Mühlbauer… - Nature …, 2014 - nature.com
Enterobacteria, especially Escherichia coli, are abundant in patients with inflammatory bowel
disease or colorectal cancer (CRC). However, it is unclear whether cancer is promoted by …

Community-wide analysis of microbial genome sequence signatures

GJ Dick, AF Andersson, BJ Baker, SL Simmons… - Genome biology, 2009 - Springer
… The extent to which palindromic tetranucleotides are avoided in both viral and microbial
genomes varies significantly and thus could be a factor in defining genome signatures (…

Horizontal gene transfer among microbial genomes: new insights from complete genome analysis

JA Eisen - Current opinion in genetics & development, 2000 - Elsevier
… , genome analysis indicates that HGT appears to have played little role in shaping Chlamydial
genomes: … Genome analysis has also lent support to one of the more interesting possible …

The integrated microbial genomes (IMG) system

VM Markowitz, F Korzeniewski… - Nucleic acids …, 2006 - academic.oup.com
… IMG provides support for comparative analysis of microbial genomes in an integrated genome
data context. This requires a high level of genome diversity from public sources, such as …

MGcV: the microbial genomic context viewer for comparative genome analysis

L Overmars, R Kerkhoven, RJ Siezen, C Francke - BMC genomics, 2013 - Springer
genomic property to exploit in genome analyses. Nine years ago we developed a Microbial
Genome … to create an adaptable interactive Microbial Genome context Viewer with high …

IMG: the integrated microbial genomes database and comparative analysis system

VM Markowitz, IMA Chen, K Palaniappan… - Nucleic acids …, 2012 - academic.oup.com
… The Integrated Microbial Genomes (IMG) system integrates publicly available draft and
complete microbial genomes from all three domains of life with a large number of plasmids and …

[图书][B] Comparative genome analysis in the integrated microbial genomes (IMG) system

VM Markowitz, NC Kyrpides - 2008 - Springer
Microbial genome analysis is a growing area that is expected to lead to advances in …
According to the Genomes Online Database, as of April 2007 close to 500 microbial genomes have …