Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents

JM Roosenberg II, YM Lin, Y Lu… - Current medicinal …, 2000 - ingentaconnect.com
… (microbial iron chelators) play an extremely important role in microbial pathogenicity. …
specific low molecular weight iron chelators called siderophores to sequester and solubilize …

[HTML][HTML] Harnessing microbial iron chelators to develop innovative therapeutic agents

M Ribeiro, CA Sousa, M Simões - Journal of Advanced Research, 2022 - Elsevier
Microbial iron chelators as a new … iron chelators and their biosynthesis is driven by the iron
concentration in the surrounding environment. These iron chelators are secreted out for iron

[PDF][PDF] Production of microbial iron chelators (siderophores) by fluorescent Pseudomonads

RZ Sayyed, MD Badgujar, HM Sonawane, MM Mhaske… - 2005 - researchgate.net
Two fluorescent pseudomonads, Pseudomonas fluorescens NCIM 5096 and P. putida
NCIM 2847 produced maximum yield of hydroxamate type of siderophore (87 & 83% units, …

The role of iron and chelators on infections in iron overload and non iron loaded conditions: prospects for the design of new antimicrobial therapies

GJ Kontoghiorghes, A Kolnagou, A Skiada… - …, 2010 - Taylor & Francis
… mammalian hosts, which is primarily accomplished by the iron chelating proteins transferrin
and lactoferrin. Chelating drugs could prevent microbial growth and play an essential role in …

[HTML][HTML] Iron pathways and iron chelation approaches in viral, microbial, and fungal infections

R Chhabra, A Saha, A Chamani, N Schneider, R Shah… - Pharmaceuticals, 2020 - mdpi.com
… such as viruses, microbes, and fungi to uptake iron from sources in the host are discussed
in this review, along with the effect of iron chelators which may potentially antagonize their …

Microbial iron chelators as drug delivery agents: the rational design and synthesis of siderophore-drug conjugates

MJ Miller, F Malouin - Accounts of chemical research, 1993 - ACS Publications
… of iron, many microbes synthesize and excrete powerful ferric ion-selective chelating agents…
1 These sequestering agents facilitate active transport of chelated iron into cells where, by …

Structures, coordination chemistry and functions of microbial iron chelates

BF Matzanke - Handbook of Microbial Iron Chelates (1991), 2017 - taylorfrancis.com
… In addition, many ferric and ferrous iron chelating agents of microbial origin have been
detected for which the biological role is yet unclear. One group of these compounds, the …

Microbial iron-chelators and their action on Klebsiella infections in the skin of guinea-pigs.

PL Khimji, AA Miles - British journal of experimental pathology, 1978 - ncbi.nlm.nih.gov
… The virulence of 6 strains was enhanced by ferric iron (E+ strains). Guinea-… iron and by two
microbial iron-chelators-catecholes extracted from klebsiellae, and the Streptomyces chelator

[HTML][HTML] Synthesis, nature and utility of universal iron chelator–Siderophore: A review

A Khan, P Singh, A Srivastava - Microbiological research, 2018 - Elsevier
… are ferric ion specific chelators secreted under iron stressed condition. These non-… other
heavy metal chelation have increased in past decade. The iron chelation ability of siderophores …

Microbial iron chelators: A sustainable tool for the biocontrol of plant diseases

SB Chincholkar, BL Chaudhari, SK Talegaonkar… - Biocontrol Potential and …, 2000 - Springer
… Based on this theme, use of microbial iron chelators / sidero phores is reviewed. It has started
on a positive consideration of healthy plant as an ecological asset and for its preservation …