Antitumor effects of fecal microbiota transplantation: Implications for microbiome modulation in cancer treatment

H Xu, C Cao, Y Ren, S Weng, L Liu, C Guo… - Frontiers in …, 2022 - frontiersin.org
… of human gut microbiota in tumor development. Likewise, we will discuss the antitumor
effect and clinical application of FMT by modulating or reconstructing intestinal microbiota, …

Microbiota transplantation: targeting cancer treatment

X Wu, T Zhang, X Chen, G Ji, F Zhang - Cancer letters, 2019 - Elsevier
… with tumors, reconstruction of gut microbiota by transplanting related “favorable” bacterium
(the step 1 and step 2 of step-up MT) may promote the anti-tumor effect and/or reduce the …

Effects of microbiota on anticancer drugs: Current knowledge and potential applications

J Huang, W Liu, W Kang, Y He, R Yang, X Mou… - …, 2022 - thelancet.com
… of microbiota which facilitates the efficacy of immune checkpoint inhibitors. Moreover, we …
several microbiota-modulating strategies including fecal microbiota transplantation and …

Intestinal microbiota: a novel target to improve anti-tumor treatment?

R Villéger, A Lopès, G Carrier, J Veziant… - International journal of …, 2019 - mdpi.com
… reuteri inhibited the development and progression of ICI therapy-associated colitis in
melanoma tumor-bearing mice without affecting the antitumor effect of the immunotherapy. …

Gut microbiota and antitumor immunity: potential mechanisms for clinical effect

EN Baruch, J Wang, JA Wargo - Cancer Immunology Research, 2021 - AACR
… 5), the specific mechanisms through which the microbiota affects immunity and responses to
microbiota affects antitumoral immune activity. We also discuss the impact of gut microbiota

Fecal microbiota transplantation: a promising strategy in preventing the progression of non-alcoholic steatohepatitis and improving the anti-cancer immune response

V Delaune, LA Orci, S Lacotte, A Peloso… - Expert opinion on …, 2018 - Taylor & Francis
… composition of the gut microbiota (henceforth referred to as … potential benefits of fecal
microbiota transplantation (FMT) in … The anti-tumoral effect of PD-1/PD-L1 blockade is dependent …

Fecal microbiota transplantation in cancer management: Current status and perspectives

D Chen, J Wu, D Jin, B Wang… - International journal of …, 2019 - Wiley Online Library
… , Bifidobacterium was identified to facilitate the effects of PD-L1 treatment.72 Lately, a study
of … Thus, FMT seems to be promising in enhancing antitumor immunity in melanoma patients …

Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy

M Uribe-Herranz, S Beghi, M Ruella, K Parvathaneni… - Molecular Therapy, 2023 - cell.com
… Based on these data, in the present study, we explore how modulation of the gut microbiota
using vancomycin affects the outcomes of CART-19 therapy. We analyzed the effect of …

The impact of modulating the gastrointestinal microbiota in cancer patients

E Morkūnas, J Skiecevičienė, J Kupčinskas - Best Practice & Research …, 2020 - Elsevier
effects of modulating gastrointestinal microbiota in cancer patients. This paper reviews
effects of … Preclinical and clinical studies demonstrated that antibiotics modulate the antitumor

Gut microbiota and cancer: How gut microbiota modulates activity, efficacy and toxicity of antitumoral therapy

S Gori, A Inno, L Belluomini, P Bocus, Z Bisoffi… - Critical Reviews in …, 2019 - Elsevier
… To establish a cause-effect relationship between the … mice were recolonized by fecal microbiota
transplantation (FMT) using … antitumoral drugs and the host susceptibility to toxic effects. …