Fecal microbiota transplantation and emerging applications

TJ Borody, A Khoruts - Nature reviews Gastroenterology & hepatology, 2012 - nature.com
… by new research into the gut microbiota, which is now beginning … microbiota-related
dysfunction. This understanding invites the investigation of FMT for several disorders, including IBD, …

Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease

AR Weingarden, BP Vaughn - Gut microbes, 2017 - Taylor & Francis
… gut microbiota and IBD and the emerging data on FMT for IBD will be discussed. … IBD and
the gut microbiota, and then discuss the current data on fecal microbiota transplantation in IBD. …

Systematic review with meta‐analysis: faecal microbiota transplantation for the induction of remission for active ulcerative colitis

SP Costello, W Soo, RV Bryant, V Jairath… - Alimentary …, 2017 - Wiley Online Library
… Faecal microbiota transplantation (FMT) is emerging as a novel therapy for ulcerative colitis
(UC). Interpretation of efficacy of FMT for UC is complicated by differences among studies in …

Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized controlled trial

P Moayyedi, MG Surette, PT Kim, J Libertucci, M Wolfe… - Gastroenterology, 2015 - Elsevier
… A likely candidate that could drive the immune response in UC is the colonic microbiome,
as … of colitis require gut bacteria to induce inflammation. Fecal microbiota transplantation (FMT) …

[HTML][HTML] Protective role of fecal microbiota transplantation on colitis and colitis-associated colon cancer in mice is associated with Treg cells

Z Wang, W Hua, C Li, H Chang, R Liu, Y Ni… - Frontiers in …, 2019 - frontiersin.org
microbiota transplantation (FMT) on azoxymethane–dextran sodium sulfate (AOM/DSS)-induced
colitis and … (A) FMT reduced DSS-induced body weight changes. The weights of mice in …

[HTML][HTML] Fecal microbiota transplantation (FMT) alleviates experimental colitis in mice by gut microbiota regulation

W Zhang, G Zou, B Li, X Du, Z Sun, Y Sun… - … of microbiology and …, 2020 - ncbi.nlm.nih.gov
… In summary, the fecal microbiota transplantation (FMT) intervention showed protective
effects against UC in vivo by improving the levels of DAI, relieving colon pathological damages, …

[HTML][HTML] Fecal microbiota transplantation ameliorates experimentally induced colitis in mice by upregulating AhR

YL Wei, YQ Chen, H Gong, N Li, KQ Wu, W Hu… - Frontiers in …, 2018 - frontiersin.org
… Fecal microbiota transplantation reversed body weight loss and decreased the Disease
Activity Index (DAI) score of mice with acute colitis induced by DSS. (A) Experimental protocol. (B…

Beneficial effects of fecal microbiota transplantation on ulcerative colitis in mice

Z Tian, J Liu, M Liao, W Li, J Zou, X Han… - Digestive diseases and …, 2016 - Springer
… We used acute model of DSS-induced colitis because it is more amenable to tracking and
the study of specific treatment effect. Acute and chronic colitis may form a continuum of a …

Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis

L Zhang, X Ma, P Liu, W Ge, L Hu… - … Biology and …, 2021 - journals.sagepub.com
… Ulcerative colitis pathogenesis is associated with the involvement of immune cells …
microbiota transplantation on T cell cytokines in a dextran sulfate sodium-induced ulcerative colitis

Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial

S Paramsothy, MA Kamm, NO Kaakoush, AJ Walsh… - The Lancet, 2017 - thelancet.com
microbiota transplantation is a novel form of therapeutic microbial manipulation, but its efficacy
in ulcerative colitis … multidonor, faecal microbiota transplantation in active ulcerative colitis. …