Therapeutic targeting of the prostate cancer microenvironment
M Karlou, V Tzelepi, E Efstathiou - Nature Reviews Urology, 2010 - nature.com
… –epithelial interaction in prostate cancer will also be included… standard treatment on the
prostate cancer microenvironment. … prostate tumor cells remodel the bone microenvironment and …
prostate cancer microenvironment. … prostate tumor cells remodel the bone microenvironment and …
[HTML][HTML] The reactive stroma microenvironment and prostate cancer progression
DA Barron, DR Rowley - Endocrine-related cancer, 2012 - erc.bioscientifica.com
Reactive stroma initiates during early prostate cancer development and coevolves with
prostate cancer progression. Previous studies have defined the key markers of reactive stroma …
prostate cancer progression. Previous studies have defined the key markers of reactive stroma …
Tumor microenvironment and metabolism in prostate cancer
P Chiarugi, P Paoli, P Cirri - Seminars in oncology, 2014 - Elsevier
… cells are able to induce profound changes in their microenvironment by remodeling ECM
and secreting large amounts of chemokines, cytokines, and growth factors, which stimulate …
and secreting large amounts of chemokines, cytokines, and growth factors, which stimulate …
Regulation of prostate cancer progression by the tumor microenvironment
SL Shiao, GCY Chu, LWK Chung - Cancer letters, 2016 - Elsevier
… to myofibroblasts with a concomitant increase in the accumulation and remodeling of the
tissue ECMs. This remodeling process leads to the production and elaboration of previously …
tissue ECMs. This remodeling process leads to the production and elaboration of previously …
[HTML][HTML] Immune signature driven by ADT-induced immune microenvironment remodeling in prostate cancer is correlated with recurrence-free survival and immune …
X Long, H Hou, X Wang, S Liu, T Diao, S Lai… - Cell death & …, 2020 - nature.com
… prostate cancer (PCa). However, its potential effects on the tumor immune microenvironment
(… genes in the ADT-induced immune remodeling process. The results showed differences …
(… genes in the ADT-induced immune remodeling process. The results showed differences …
Modulation of prostate cancer growth in bone microenvironments
M Edlund, SY Sung, LWK Chung - Journal of cellular …, 2004 - Wiley Online Library
… cues for bone remodeling, as well as shifts in bone microenvironmental composition, especially
… findings on hormones, bone remodeling, aging, and prostate cancer is complex, but rich, …
… findings on hormones, bone remodeling, aging, and prostate cancer is complex, but rich, …
The role of tumor microenvironment in prostate cancer bone metastasis
C Morrissey, RL Vessella - Journal of cellular biochemistry, 2007 - Wiley Online Library
… /proliferation, reactive stroma recruitment, and bone remodeling. Each stage presents us
with possible targets for treatment. The tumor microenvironment is necessary for the survival of …
with possible targets for treatment. The tumor microenvironment is necessary for the survival of …
Molecular insights into prostate cancer progression: the missing link of tumor microenvironment
LWK Chung, A Baseman, V Assikis, HE Zhau - The Journal of urology, 2005 - Elsevier
… interaction has a decisive role in controlling local cancer growth, … in prostate cancer cells
alone are not enough to confer metastatic status without a supporting tumor microenvironment. …
alone are not enough to confer metastatic status without a supporting tumor microenvironment. …
PTEN loss promotes intratumoral androgen synthesis and tumor microenvironment remodeling via aberrant activation of RUNX2 in castration-resistant prostate cancer
… )–dependent prostate cancer, … prostate cancer cells. We further show that loss of PTEN
augments steroidogenesis gene expression, IAS and tumor microenvironment (TME) remodeling …
augments steroidogenesis gene expression, IAS and tumor microenvironment (TME) remodeling …
[HTML][HTML] Obesogenic high-fat diet and MYC cooperate to promote lactate accumulation and tumor microenvironment remodeling in prostate cancer
N Boufaied, P Chetta, T Hallal, S Cacciatore, D Lalli… - Cancer Research, 2024 - AACR
… microenvironment (TME) and drive cancer could facilitate development of precision nutrition
approaches. Using the Hi-MYC prostate cancer … –driven invasive prostate cancer through …
approaches. Using the Hi-MYC prostate cancer … –driven invasive prostate cancer through …
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