… microglia turnover in the brain and that microglia phenotype may change depending on aging,
stage of the disease, … The purpose of this review is first, to describe microglia as a cell of …

… Studies using murine models of AD have demonstrated that chemokine receptors influence
AD pathology by modulating several aspects of microglial function, such as accumulation, …

… In this review, we discuss the significance of microglial aging in Alzheimer's disease (AD). …
specifically implicate microglia. We then examine how specific microglial functions are altered …

… To synthesize the findings from disparate approaches, we propose the following hypothesis:
Microglial function is normally protective in the brain, with microglia acting as housekeeping …

… well as altered microglial-enriched … microglia function and whether microglial-associated
transcripts were specifically altered, we also performed hierarchical cluster analysis of microglial…

… microglial functions. Finally, focusing specifically on mouse models of AD, we will summarize
the roles of microglia and … or techniques which target them during this devastating disease. …

… 2 receptor EP2 restores microglial chemotaxis and Aβ clearance… signaling suppresses
beneficial microglia functions that falter … healthy microglial function and prevent progression to AD. …

… in Alzheimer’s disease) and/or genetic mutations in genes affecting microglia function drives
microglia into a state of … These functional changes have been observed in murine models of …

… Activation of microglia results in a severely altered microenvironment. This is not only …
findings linking microglial activation and AD and speculate that microglial malfunction, which …

… That there are particular subtypes of microglia specified for certain immunoregulatory functions
is probable. Is it possible that subsets of microglia function as lymphocytic equivalents of …