Fifteen‐year quest for microphthalmia‐associated transcription factor target genes
Y Cheli, M Ohanna, R Ballotti… - Pigment cell & …, 2010 - Wiley Online Library
… Microphthalmia-associated transcription factor (MITF) was initially shown to play a key
role in melanocyte differentiation through the direct transcriptional control of TYROSINASE, …
role in melanocyte differentiation through the direct transcriptional control of TYROSINASE, …
[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology
A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
… transcription factors specify discrete cell types. In melanocytes, MITF (microphthalmia-associated
transcription factor) has a dominant role that has been termed ‘master transcriptional …
transcription factor) has a dominant role that has been termed ‘master transcriptional …
[HTML][HTML] Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human tyrosinase family genes
K Yasumoto, K Yokoyama, K Takahashi… - Journal of Biological …, 1997 - ASBMB
… Their human gene promoters share the 11-base pair M box containing a CATGTG motif,
which was shown here to be bound in vitro by microphthalmia-associated transcription factor (…
which was shown here to be bound in vitro by microphthalmia-associated transcription factor (…
Microphthalmia‐associated transcription factor in the Wnt signaling pathway
H Saito, KI Yasumoto, K Takeda… - Pigment Cell …, 2003 - Wiley Online Library
… of the lymphoid-enhancing factor-1 (LEF-1)/TCF transcription factors, containing a high-mobility-group
domain (27, 28). Thus, the LEF-1/TCF transcription factors mediate a nuclear …
domain (27, 28). Thus, the LEF-1/TCF transcription factors mediate a nuclear …
[HTML][HTML] Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation
S Shibahara, K Takeda, K Yasumoto, T Udono… - Journal of Investigative …, 2001 - Elsevier
… Microphthalmia-associated transcription factor (MITF) … pigment cell-specific transcription of
the melanogenesis enzyme … is upregulated by other transcription factors, PAX3, SOX10, and …
the melanogenesis enzyme … is upregulated by other transcription factors, PAX3, SOX10, and …
[HTML][HTML] Regulation of the microphthalmia-associated transcription factor gene by the Waardenburg syndrome type 4 gene, SOX10
C Verastegui, K Bille, JP Ortonne, R Ballotti - Journal of Biological …, 2000 - ASBMB
… Microphthalmia-associated transcription factor (MITF) … the gene encoding the transcription
factor Pax3, which regulates … encoding a SRY-related transcription factor, have been reported …
factor Pax3, which regulates … encoding a SRY-related transcription factor, have been reported …
[HTML][HTML] Microphthalmia‐associated transcription factor interacts with LEF‐1, a mediator of Wnt signaling
K Yasumoto, K Takeda, H Saito, K Watanabe… - The EMBO …, 2002 - embopress.org
… associated with a nuclear mediator of the lymphoid‐enhancing factor 1 (LEF‐1)/T‐cell factors
… leucine‐zipper region of microphthalmia‐associated transcription factor (MITF) and LEF‐1. …
… leucine‐zipper region of microphthalmia‐associated transcription factor (MITF) and LEF‐1. …
The microphthalmia-associated transcription factor Mitf interacts with β-catenin to determine target gene expression
A Schepsky, K Bruser, GJ Gunnarsson… - … and cellular biology, 2006 - Taylor & Francis
… of the microphthalmia-associated transcription factor (Mitf). This transcription factor plays a
… Here we show that Mitf can redirect β-catenin transcriptional activity away from canonical …
… Here we show that Mitf can redirect β-catenin transcriptional activity away from canonical …
Microphthalmia‐associated transcription factor in melanoma development and MAP‐kinase pathway targeted therapy
C Wellbrock, I Arozarena - Pigment cell & melanoma research, 2015 - Wiley Online Library
Malignant melanoma is a neoplasm of melanocytes, and the microphthalmia‐associated
transcription factor ( MITF ) is essential for the existence of melanocytes. MITF 's relevance for …
transcription factor ( MITF ) is essential for the existence of melanocytes. MITF 's relevance for …
[HTML][HTML] Microphthalmia associated transcription factor is a target of the phosphatidylinositol-3-kinase pathway
M Khaled, L Larribere, K Bille, JP Ortonne… - Journal of Investigative …, 2003 - Elsevier
… , thereby demonstrating that microphthalmia associated transcription factor is also a … LY294002
controls microphthalmia associated transcription factor at the transcriptional level through …
controls microphthalmia associated transcription factor at the transcriptional level through …
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