Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-κB ligand signaling
… marrow-derived precursor cells blocked for p38 MAPK activity and the mi/mi … p38 MAPK in
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
Microphthalmia‐associated transcription factor in melanoma development and MAP‐kinase pathway targeted therapy
C Wellbrock, I Arozarena - Pigment cell & melanoma research, 2015 - Wiley Online Library
… of melanoma to current treatments using MAPK pathway targeting drugs, this review will
also address the role of MITF in melanoma development and BRAF/MEK inhibitor therapy. …
also address the role of MITF in melanoma development and BRAF/MEK inhibitor therapy. …
[HTML][HTML] … by 8-methoxypsoralen: the involvement of microphthalmia-associated transcription factor, the protein kinase a signal pathway, and proteasome-mediated …
… levels of microphthalmia-associated transcription factor and … stimulated microphthalmia-associated
transcription factor … of microphthalmia-associated transcription factor expression …
transcription factor … of microphthalmia-associated transcription factor expression …
Melanocytes and the Microphthalmia Transcription Factor Network
E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
… of Wnt signaling, cAMP signaling may also affect Mitf function through the MAP kinase
pathway or the PI3K pathway (… Treatment of osteoclasts with Rankl results in p38 MAPK-mediated …
pathway or the PI3K pathway (… Treatment of osteoclasts with Rankl results in p38 MAPK-mediated …
MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes
TJ Hemesath, ER Price, C Takemoto, T Badalian… - Nature, 1998 - nature.com
… 1), constitutively active Raf plus wild-type MEK were used to achieve sustained activation of
the MAPK pathway and permit measurable accumulation of luciferase. Co-transfection of Raf…
the MAPK pathway and permit measurable accumulation of luciferase. Co-transfection of Raf…
The underestimated role of the microphthalmia-associated transcription factor (MiTF) in normal and pathological haematopoiesis
A Oppezzo, F Rosselli - Cell & Bioscience, 2021 - Springer
… Following a stress that causes a need for new cells to replenish BM and/or circulating
blood, the p38 MAPK pathway is activated in HSCs, with p38α promoting cell cycle entry and …
blood, the p38 MAPK pathway is activated in HSCs, with p38α promoting cell cycle entry and …
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
JJ Hsiao, DE Fisher - Archives of biochemistry and biophysics, 2014 - Elsevier
… pathway, the MAPK pathway, and the PI3K pathway. PAX3, SOX10, PGC1, LEF, and CREB
are some of the known transcription factors … by MAPK, ribosomal S6 kinase (RSK), and p38. C…
are some of the known transcription factors … by MAPK, ribosomal S6 kinase (RSK), and p38. C…
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
A Oppezzo, J Bourseguin, E Renaud… - The Journal of …, 2020 - Am Soc Clin Investig
… of the transcription factor microphthalmia (MiTF) through the cooperative, unscheduled
activation of several stress-signaling pathways, including the SMAD2/3, p38 MAPK, NF-κB, and …
activation of several stress-signaling pathways, including the SMAD2/3, p38 MAPK, NF-κB, and …
Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors
… The microphthalmia-associated transcription factor (MITF) is required for terminal osteoclast
differentiation and is a target for signaling pathways engaged by colony stimulating factor (…
differentiation and is a target for signaling pathways engaged by colony stimulating factor (…
Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation
DM Molina, S Grewal, L Bardwell - Journal of Biological Chemistry, 2005 - ASBMB
… specific signaling by mitogen-activated protein kinases (MAPKs) … Here we show that the
MAPKs ERK1 and ERK2 form a … substrate the microphthalmia-associated transcription factor (…
MAPKs ERK1 and ERK2 form a … substrate the microphthalmia-associated transcription factor (…
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