Nanocarriers for microRNA delivery in cancer medicine

I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
… of nanomedicine to cancer therapy. This review covers the different miRNA therapeutic
strategies and delivery challenges for its application in cancer medicine. Current trends in …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
… , and developed a battery of viral and nonviral delivery … are a limited number of
microRNA-based applications that have … into viable microRNA-based clinical tools for cancer

MicroRNA delivery for regenerative medicine

B Peng, Y Chen, KW Leong - Advanced drug delivery reviews, 2015 - Elsevier
delivery platforms [25]. The aim of this review is to capture the state-of-art of miRNA delivery
systems and highlight their design consideration from the regenerative medicine perspective…

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
… significant hurdles in therapeutic miRNA usage are the stability and the delivery system. In
… of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery (…

miRNA: the new frontier in cancer medicine

J Ju, J Jiang, A Fesler - Future medicinal chemistry, 2013 - Taylor & Francis
delivery systems Citation[20]. Exosomal delivery, offers a unique opportunity for miRNA
delivery … We remain optimistic about the miRNA-based diagnosis and future medicine in cancer. …

Scaffold‐based microRNA therapies in regenerative medicine and cancer

CM Curtin, IM Castaño… - Advanced healthcare …, 2018 - Wiley Online Library
… This section focuses on miRNA delivery vectors which have been considered for the
development of scaffold-based miRNA delivery systems, their design and characteristics. …

[HTML][HTML] Nanoparticles as drug delivery systems in cancer medicine: emphasis on RNAi-containing nanoliposomes

MR Díaz, PE Vivas-Mejia - Pharmaceuticals, 2013 - mdpi.com
… of nanoliposomes for the delivery of small interference RNA (siRNA) and microRNA (miRNAs)-based
molecules including their use in current clinical trials for cancer treatment. …

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

J Kota, RR Chivukula, KA O'Donnell, EA Wentzel… - Cell, 2009 - cell.com
… efficacy of a miRNA replacement therapy for liver cancer. We demonstrate … , a miRNA that
is normally expressed at high levels in diverse tissues. Expression of this miRNA in liver cancer

Challenges identifying efficacious miRNA therapeutics for cancer

M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
miRNA therapeutics will have a major part in cancer therapy in the future. Specifically,
personalized cancer medicine can be accomplished by constructing the unique miRNA mimic or …

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
… viral synthetic miRNA vectors and the promise of miRNA-based … the delivery obstacles, and
the development of miRNA delivery … dramatically growing interest in miRNA-based medicine. …