Exosome based miRNA delivery strategy for disease treatment

Z Fang, X Zhang, H Huang, J Wu - Chinese Chemical Letters, 2022 - Elsevier
… is mainly used in cancer treatment, nerve regeneration, … medicine, so this chapter mainly
introduces the research progress of exosomes as miRNA vectors when treating cancer, …

[HTML][HTML] Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer

SKD Dwivedi, SB Mustafi, LS Mangala, D Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… better response compared to either cisplatin alone or any single microRNA in combination
with cisplatin. With the advent of miRNA replacement therapy some of which are in Phase 2 …

[HTML][HTML] Comparison of oncolytic virotherapy and nanotherapy as two new miRNA delivery approaches in lung cancer

AG Alvanegh, SM Ganji, M Tavallaie, A Rafati… - Biomedicine & …, 2021 - Elsevier
… In this study, the authors investigated the miRNA expression profiles in human lung cancer
and miRNA regulation by an epigenetic mechanism. They demonstrated that the miRNA

MicroRNA therapeutics: the next magic bullet?

B Simonson, S Das - Mini reviews in medicinal chemistry, 2015 - ingentaconnect.com
… of microRNAs is a promising area of study for therapeutics. Here we review the current
knowledge of microRNA … methods of delivery of miRNA, and current clinical trials of microRNA-…

[HTML][HTML] Methods of miRNA delivery and possibilities of their application in neuro-oncology

I Gareev, O Beylerli, T Rasim, T Ilyasova… - Non-coding RNA …, 2023 - Elsevier
… methods for delivering miRNA agents to brain tumor cells. We will explore the advantages
and disadvantages of different delivery systems and consider some clinical aspects of miRNA-…

Therapeutic strategies for miRNA delivery to reduce hepatocellular carcinoma

B Roy, S Ghose, S Biswas - Seminars in Cell & Developmental Biology, 2022 - Elsevier
… and that of their delivery systems. Here we provide a comprehensive update describing
various miRNA delivery systems, including virus-based delivery and non-viral delivery. The latter …

MicroRNA-nanoparticles against cancer: Opportunities and challenges for personalized medicine

E Martino, N D'Onofrio, C Anastasio, M Abate… - … Therapy-Nucleic Acids, 2023 - cell.com
… a promising strategy in cancer treatment. In the present review, we discuss the latest advances
in the field of miRNA-encapsulating NPs in cancer, focusing on colorectal cancer and its …

Progress in systemic co-delivery of microRNAs and chemotherapeutics for cancer treatment by using lipid-based nanoparticles

W He, A Turkeshi, X Li, H Zhang - Therapeutic delivery, 2020 - Taylor & Francis
… with chemotherapeutics to treat cancer. In this Special Report, we discuss the significance
of systemic co-delivery of chemotherapeutics and miRNA therapeutics for cancer therapy and …

RNAi-based therapeutics and tumor targeted delivery in cancer

G Kara, GA Calin, B Ozpolat - Advanced drug delivery reviews, 2022 - Elsevier
… tool for targeted therapies and precision medicine. siRNA and miRNA-based therapies have
… be provoked upon systemic siRNA or miRNA delivery to eliminate these RNAs and hinder …

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

MV Iorio, CM Croce - EMBO molecular medicine, 2012 - embopress.org
… expressed microRNAs are a hallmark of several diseases like cancer. MicroRNA expression
… Here, we review our current knowledge about the involvement of microRNAs in cancer, and …