MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies

T Kim, CM Croce - Experimental & molecular medicine, 2023 - nature.com
… and context-dependent functions in different types of cancer 13 . In addition to the general
functions of miRNAs in cancer, each cancer type features unique miRNA expression patterns. …

miRNA-based therapies: strategies and delivery platforms for oligonucleotide and non-oligonucleotide agents

V Baumann, J Winkler - Future medicinal chemistry, 2014 - Taylor & Francis
miRNA mimics delivered with PLGA have been reported, oligonucleotides for antagonizing
miRNAs have been successfully delivered … silica nanoparticles for miRNA delivery resulted in …

Nanoparticle-mediated delivery of therapeutic genes: focus on miRNA therapeutics

M Muthiah, IK Park, CS Cho - Expert opinion on drug delivery, 2013 - Taylor & Francis
… This study verified that polymeric carriers can be efficiently utilized for antimetastatic miRNA
delivery to suppress metastasis, as well as for miRNA delivery of tumor suppressor proteins. …

Liposomal delivery of microRNA-7–expressing plasmid overcomes epidermal growth factor receptor tyrosine kinase inhibitor-resistance in lung cancer cells

K Rai, N Takigawa, S Ito, H Kashihara, E Ichihara… - Molecular cancer …, 2011 - AACR
… To develop a new approach for the suppression of EGFR, we focused on microRNA (miRNA
EGFR-TKI and anti-EGFR antibodies, miRNA is expected to be independent of unexpected …

MicroRNAs and cancer: towards a personalized medicine

M Fabbri - Current Molecular Medicine, 2013 - ingentaconnect.com
cancer and to prognosticate clinical outcome and response to treatment of tumors. The
advent of miRNA mimic and miRNA silencing molecules has allowed to modulate miRNA

MicroRNAs (miRNAs) in cancer invasion and metastasis: therapeutic approaches based on metastasis-related miRNAs

A Aigner - Journal of molecular medicine, 2011 - Springer
… of miRNA action, this review article describes the roles of miRNAs in cancer invasion and …
of the delivery of miRNA-based therapeutics as novel strategy in antimetastatic treatment. …

Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy

Y Chen, X Zhu, X Zhang, B Liu, L Huang - Molecular therapy, 2010 - cell.com
… of systemic delivery of miRNA for cancer therapy by using a targeted gene delivery system.
… As far as we know, this is also the first report of co-delivery of miRNA and siRNA as cancer

Updates and current challenges in microRNA research for personalized medicine in ovarian cancer

V Mandilaras, M Vernon… - Expert Opinion on …, 2017 - Taylor & Francis
… Long primary-microRNAs (pri-miRNAs) … -miRNA into precursor miRNA (2) (pre-miRNA)
which is later exported out of the nucleus by exportin 5 (3). Once in the cytoplasm, the pre-miRNA

[HTML][HTML] MicroRNA delivery systems in glioma therapy and perspectives: A systematic review

JM Jiménez-Morales, YE Hernández-Cuenca… - Journal of Controlled …, 2022 - Elsevier
… of various delivery systems for exogenous miRNA administration… In the last decade, miRNA
delivery systems have provided … making the transition to precision translational medicine [21]. …

Exploring the potential of engineered exosomes as delivery systems for tumor-suppressor microRNA replacement therapy in ovarian cancer

M Kobayashi, K Sawada, M Miyamoto… - Biochemical and …, 2020 - Elsevier
… up by cancer cells, indicating that they can serve as a miRNA … a carrier for miRNA replacement
therapy for ovarian cancer (OC… the development of personalized medicine for OC patients. …