Microsatellite instability: an update

H Yamamoto, K Imai - Archives of toxicology, 2015 - Springer
… mutator phenotype known as microsatellite instability (MSI), … sequences that are called
microsatellites. Lynch syndrome is … Recent comprehensive molecular characterizations of CRC, …

Microsatellite instability in colorectal cancer

CR Boland, A Goel - Gastroenterology, 2010 - Elsevier
… It is not clear which model occurs during CRC pathogenesis, but at least 1 type of colorectal
tumor is caused by the hypermutable phenotype known as microsatellite instability (MSI). …

[HTML][HTML] Microsatellite instability in colorectal cancer

LA Gian, B Lorena, A Cinzia, L Gioacchino… - Acta Bio Medica …, 2018 - ncbi.nlm.nih.gov
… Owing to their repeated structure, microsatellites are particularly prone to replication …
microsatellite instability (MSI), characterized by widespread length polymorphisms of microsatellite

[HTML][HTML] The immune biology of microsatellite-unstable cancer

M Kloor, M von Knebel Doeberitz - Trends in cancer, 2016 - cell.com
Microsatellite instability in colorectal cancer. … Microsatellite instability in colorectal cancer.
Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and …

Microsatellite instability in colorectal carcinoma: The comparison of immunohistochemistry and molecular biology suggests a role for hMLH6 immunostaining

V Rigau, N Sebbagh, S Olschwang… - … of pathology & …, 2003 - meridian.allenpress.com
Context.—Microsatellite instability (MSI) due to defective mismatch repair (MMR) genes has
been reported in the majority of colorectal tumors from patients with hereditary nonpolyposis …

Microsatellite instability in colorectal cancer

B Iacopetta, F Grieu, B Amanuel - Asia‐Pacific Journal of …, 2010 - Wiley Online Library
… defined by widespread alterations in the size of DNA microsatellite regions, usually mono-,
di-, or trinucleotide repeats. This so-called microsatellite instability (MSI) is due to a defective …

Microsatellite instability in colorectal cancer—the stable evidence

E Vilar, SB Gruber - Nature reviews Clinical oncology, 2010 - nature.com
Microsatellite instability (MSI) is the molecular fingerprint of a deficient mismatch repair
system. Approximately 15% of colorectal cancers (CRC) display MSI owing either to epigenetic …

Molecular key to understand the gastric cancer biology in elderly patients—the role of microsatellite instability

K Polom, D Marrelli, G Roviello… - Journal of Surgical …, 2017 - Wiley Online Library
Background and Objectives Microsatellite instability (MSI) in gastric cancer (GC) is associated
with older age. We present the clinicopathological results of younger and older patients …

[HTML][HTML] Correlations between microsatellite instability and the biological behaviour of tumours

G Yang, R Zheng, Z Jin - Journal of cancer research and clinical oncology, 2019 - Springer
… level microsatellite instability often show a better efficacy and prognosis than those with low-level
microsatellite instability or stable microsatellites… , microsatellite instability often results in …

Microsatellite instability in colorectal cancer

K Söreide, EAM Janssen, H Söiland… - Journal of British …, 2006 - academic.oup.com
… cancer in most patients, and two distinct pathways have been identified—the microsatellite
instability (MSI) and the chromosomal instability (CIN) pathways 2–6 . Discovery of these two …