… mice as a genetic mouse model of migraine and mice … (EP2-/- mice) or in the glycine receptor
α3 subunit (GlyRα3-/- mice), … cortical dysfunctions associated with migraine in freely moving …

… The migraine aura is caused by “cortical spreading … which can be considered a model
synapse to study effects of Ca v … that the FHM1 mice are useful in vivo models to study migraine …

… of CSD in FHM1 mutant mice, we investigated cortical neurotransmission in neuronal … cortical
synapses as the basis for facilitated spreading depression in Cav2.1 knockin migraine mice…

… both pre- and post-synaptic cortical mechanisms [33], whether … pain in mice (consistent with
headache provocation in humans) [… of CGRP to the rat or mouse meninges does in fact cause …

… mouse model can be utilized to broaden our understanding of generalized epilepsy and
comorbidity hereof in migraine… Impairments in astrocytic glutamate uptake from the synaptic cleft …

… synaptic mechanisms within sensory circuits that might underlie the migraine relevant
phenotypes of CK1δ T44A mice… membrane potential variance during sensory cortical “up states” …

… you measure migraine in a mouse? Of course, we cannot fully recapitulate migraine in a
mouse, … Hence, CGRP may act by sensitizing synapses in the CNS, and that over-sensitization …

… that cortical LTPs contribute to migraine-related pain and anxiety. Drugs that inhibit cortical
excitation such as NB001 may serve as potential medicines for treating migraine in the future. …

… Migraine Type 1 (FHM1), result in enhanced cortical glutamatergic transmission and a higher
susceptibility to cortical … glial cell cultures of FHM1 mutant mice. Hence, we hypothesize …

… aura and it has been implicated in the generation of migraine headache. Cortical excitability
can … Recordings of spontaneous excitatory and inhibitory post-synaptic currents in pyramidal …