Secretion of bovine αlactalbumin into the milk of transgenic rats

SI Hochi, T Ninomiya, M Waga‐Homma… - Molecular …, 1992 - Wiley Online Library
… Out of 17 transgenic rat lines, 11 secreted baLA into their milk at concentrations … rat models
of animal bioreactors. This report shows a high level secretion of baLA into transgenic rat milk

Variation in expression of a bovine α-lactalbumin transgene in milk of transgenic mice

GT Bleck, RD Bremel - Journal of dairy science, 1994 - Elsevier
… of a-LA in the milk of transgenic mice at levels comparable with those in bovine milk. This …
Tissue-specific, high level expression of the rat whey acidic protein gene in transgenic mice. …

[HTML][HTML] Expression and characterization of bioactive recombinant human α-lactalbumin in the milk of transgenic cloned cows

J Wang, P Yang, B Tang, X Sun, R Zhang, C Guo… - Journal of dairy …, 2008 - Elsevier
… The transgene construct containing 6.5 kbp of 5′ flanking … α-LA in transgenic cow milk. In
this study, the expression level in transgenic cows was comparable with that in transgenic rats

Position‐independent and high‐level expression of human αlactalbumin in the milk of transgenic rats carrying a 210‐kb YAC DNA

Y Fujiwara, M Miwa, R Takahashi… - Molecular …, 1997 - Wiley Online Library
… Some studies showed expression of transgenes in tissues other than the mammary gland (…
human α-lactalbumin expression in tissues other than the mammary glands of transgenic rats, …

Production of proteins in the milk of transgenic livestock: problems, solutions, and successes

A Colman - The American journal of clinical nutrition, 1996 - Elsevier
… methods can also be used to study the molecular basis of milk biogenesis. The effect on
milk production in mice with all endogenous alpha-lactalbumin genes removed and in mice in …

Expression of recombinant human α-lactalbumin in milk of transgenic cloned pigs is sufficient to enhance intestinal growth and weight gain of suckling piglets

J Ma, Q Li, Y Li, X Wen, Z Li, Z Zhang, J Zhang, Z Yu… - Gene, 2016 - Elsevier
… A study on feeding rats by administering bovine α-LA hydrolysates demonstrated that the
secretion of glucagon-like peptide 2 (GLP-2) was increased and small intestinal growth was …

Efficient tissue‐specific expression of bovine αlactalbumin in transgenic mice

JL VILOTTE, S Soulier, MG STINNAKRE… - European journal of …, 1989 - Wiley Online Library
milk protein genes have been incorporated into transgenic mice: sheep ,&lactoglobulin [I]
and rat p-… transferase interacts with rat a-lactalbumin [23]. Therefore, expression of the bovine …

Nutritional and physiologic significance of α-lactalbumin in infants

B Lönnerdal, EL Lien - Nutrition Reviews, 2003 - academic.oup.com
… level expression of human alpha-lactalbumin in the milk of transgenic rats carrying a 210-kb …
of alphalactalbumin in transgenic mice on milk yield and pup growth. J Dairy Sci. 2001;84:…

Abnormal properties of milk from transgenic mice expressing bovine β-casein under control of the bovine α-lactalbumin 5′ flanking region

GT Bleck, R Jiménez-Flores, RD Bremel - International Dairy Journal, 1995 - Elsevier
… of genes in transgenic animals, we chose to test the ability of the bovine a-lactalbumin
using the rat /?-casein promoter and the hormone response elements of mouse mammary …

Transgenic over-expression of bovine α-lactalbumin and human insulin-like growth factor-I in porcine mammary gland

SM Donovan, MH Monaco, GT Bleck, JB Cook… - Journal of Dairy …, 2001 - Elsevier
… Effects in rats of dietary protein inadequacy on lactose production, milk volume and
component of the lacY tose synthetase complex (EC 2.4.1.22). ann nutr. Metab. 31:179Y184. …