… The milk to plasma (m/p) concentration ratio of drugs is used to estimate the amount of drug
… Presently, the milk to plasma concentration ratio (m/p ratio) is one of the most widely used …

… (b) The pK a of a drug in plasma is the same as the pK a in milk (taken as the pK a in water).
… any drug has been determined in plasma, and so there is no basis for taking pK a in plasma …

… The classification of drugs was done according to their milk/plasma concentration ratio (M/P)
by using counter propagation artificial neural network (CP-ANN). The features of each drug …

… All drugs pass into milk to some extent. The milk:plasma (M/P) ratio based on the areas
under the respective concentration-time curves (AUCs) is useful to calculate likely infant …

… milk composition occur during the course of lactation in women.'* The following factors have
… drug transport into milk:I3 milk and plasma pH; milk and plasma protein binding; and milk fat …

… The milk: plasma concentration ratio for phenacetin in subject 1 varied between 0.4 and 0.9,
… ratio of milk to plasma was 0.7. For subject 2 (Table II) the milk: plasma concentration ratio …

… to predict/classify milk-to-plasma (M/P) drug concentration ratio remains a challenging object…
a new algorithm, was constructed to distinguish the potential risk of drugs to nursing infants. …

… period on drug interactions with milk constituents, as well as the effect on MIP. The relationship
of … in skim milk and serum protein binding and milk fat partitioning with serum and milk …

… Blood and milk samples were collected prior to drug administration (0); after 15, 30, 45, 60,
… ratio and the milk and plasma pharmacokinetics of amoxicillin after IM administration in dairy …

… plasma concentrations (as well as the estimated dose in milk… pharmacologic properties of
a drug. This review addresses … the M/P ratio and hence the amount of drug in breast milk. The …