Molecular minimal residual disease in acute myeloid leukemia

M Jongen-Lavrencic, T Grob… - … England Journal of …, 2018 - Mass Medical Soc
minimal residual disease after treatment to predict disease relapse in patients with AML has
been explored, but assessment of molecular minimal residual disease … only a few leukemia-…

Minimal residual disease in acute myeloid leukaemia

CS Hourigan, JE Karp - Nature reviews Clinical oncology, 2013 - nature.com
… Our understanding of heterogeneity and the underlying disease biology of acute myeloid
leukaemia (AML) has been greatly deepened by modern laboratory advances 1,2,3,4 that have …

Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for “prime time”?

D Grimwade, SD Freeman - … Journal of the American Society of …, 2014 - ashpublications.org
… has become apparent that acute myeloid leukemia (AML) is … transplant practice in this
disease remains largely based on … levels of leukemia (ie, minimal residual disease, MRD) using …

Minimal residual disease in acute myeloid leukemia: coming of age

E Paietta - Hematology 2010, the American Society of …, 2012 - ashpublications.org
… (MRD), defined as any measurable disease or leukemia … AML is lagging behind acute
lymphoblastic leukemia with … disadvantaged compared with acute lymphoblastic leukemia in that …

Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia

F Buccisano, L Maurillo, MI Del Principe… - Blood, The Journal …, 2012 - ashpublications.org
… In this view, measure of minimal residual disease (MRD) promises to be an efficient tool to
establish on an individual basis the patient's leukemia's susceptibility to treatment, enhancing …

Monitoring of minimal residual disease in acute myeloid leukemia

W Kern, C Haferlach, T Haferlach… - … International Journal of …, 2008 - Wiley Online Library
minimal residual disease (MRD) and to guide risk-adapted management in acute myeloid
leukemia (AML). … Treatment of patients with acute myeloid leukemia (AML) increasingly follows …

Minimal residual disease in acute myeloid leukemia—current status and future perspectives

S Kayser, RB Walter, W Stock, RF Schlenk - Current hematologic …, 2015 - Springer
… High prognostic impact of flow cytometric minimal residual disease detection in acute
myeloid leukemia: data from the HOVON/SAKK AML 42A study. J Clin Oncol. 2013;31(31):3889–97…

Relation of clinical response and minimal residual disease and their prognostic impact on outcome in acute myeloid leukemia

X Chen, H Xie, BL Wood, RB Walter… - Journal of Clinical …, 2015 - ascopubs.org
… Both presence of minimal residual disease (MRD) and achievement of complete remission
(… CR after induction therapy predict relapse in acute myeloid leukemia (AML). These results …

Minimal residual disease in acute myelogenous leukemia

NM Cruz, N Mencia‐Trinchant… - … journal of laboratory …, 2017 - Wiley Online Library
… Treatment of acute myelogenous leukemia (AML) over the past four decades remains … It is
thought that relapse in AML is in part driven by minimal residual disease (MRD) that remains in …

Minimal residual disease in acute myeloid leukemia: still a work in progress?

F Mosna, D Capelli, M Gottardi - Journal of Clinical Medicine, 2017 - mdpi.com
… use of minimal residual disease measurements in “real-… minimal residual disease will soon
become the new standard for evaluating response in the treatment of acute myeloid leukemia