… the effects of mirex and chlordecone on the uptake or transport of organic anions across
the basolateral domain of the plasma membrane into isolated rat hepatocytes. The two endog…

… in vivo of mirex in PPs as compared to DP hepatocytes (Charles et al., 1985). We report here
the in vitro kinetics of mirex binding by both DP and PP hepatocytes. A preliminary report of …

… mirex was fed, liver cells … mirex was fed, liver cells were enlarged and multinucleate and
bile stasis was evident. Electron microscopic examination of livers from rats fed 25 ppm of mirex …

… Thus, DMN, a "genotoxic" carcinogen, induces the premature appearance and selective
proliferation of tetraploid hepatocytes, while mirex had no effect on polyploidization, indicating a …

… , 10 ppm mirex (M), or M plus CD ( IO ppm each; MCD) for 15 days. On Day 15 the rats received
a … Light microscopic examination of tissues revealed swollen hepatocytes (balloon cells), …

… well as swollen and necrotic hepatocytes. Volume density of hepatocytes with each of these
morphologic features was separately determined. Morphometric data for individual rats were …

… Rats fed mirex in the diet for 166 days had minimal pathological changes intheir livers with
… of liver cells, cytoplasmicinclusions and biliary stasis with 25 ppm. Rats given 5 ppm mirex in …

… However, hepatocytes in centrolobular zones from Mirexexposed rats exhibited numerous
… and EL Benedetti: Changes in the fine structure of rat liver cells brought about by …

… laying hens fed 300 and 600 ppm mirex in their diet for 16 weeks … on the oral toxicity of mirex
in rats, including effects on … livers of male rats still showed slightly enlarged liver cells. This …

… gene (mdr) reaches high levels in the "initiated" hepatocytes during carcinogenesis and also
in the proliferating normal rat hepatocytes. As a result, cells of the regenerating liver exhibit …