… -21 occurred in gemcitabine-resistant MDA-MB-231 breast cancer cells [10] so miR-21 may
be critical to gemcitabine resistance. To … between miR-21 and gemcitabine resistance and …

… from gemcitabine-resistant L3.6pl cells (L3.6pl Gres -SP) cells were orthotopically implanted
in nude mice with or without miRNA-21 and miRNA-… of both miRNAs following gemcitabine-…

… cytotoxic chemotherapeutic agents, such as gemcitabine, docetaxel, temozolomide and …
miR21 and its function in human cancer-particularly its involvement in anticancer drug resistance…

… CAFs and Gemcitabine Resistance in PDAC To investigate whether miR-21 actively regulates
… and leads to gemcitabine resistance, we first correlated the miR-21 expression level with …

… and contributes to invasion and gemcitabine resistance in pancreatic ductal … miR-21
expression was associated with the overall survival (OS) of PDAC patients treated with gemcitabine …

… GAS5 inhibited gemcitabine resistance in pancreatic cancer by regulating miR-21.
Overexpression … resistant transporters expression. These findings have revealed the mechanisms …

… Background/Aim: Overexpression of microRNA-21 (miR-21) … to gemcitabine through the
down-regulation of miR-21 in human … down-regulation of miR-21 by I3C on gemcitabine-induced …

… Here, we found that miR-21 expression is upregulated in gemcitabine-resistant cell lines (…
compared with gemcitabine-sensitive BxPC-3 cells and that the expression of miR-21 could be …

… whether miR-217 modulates the sensitivity to gemcitabine in … that miR-217 is among the
downregulated miRNAs in human … miR-217 expression ameliorates response to gemcitabine, as …

… with GEM-resistant pancreatic ductal carcinoma. GEM-treated CAFs in PC highly secrete
multiple miRNAs such as miR-21 to promote cell proliferation and GEM drug resistance of PC. …