[HTML] mdpi.com

[HTML][HTML] Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics

M Zare, R Pemmada, M Madhavan, A Shailaja… - Pharmaceutics, 2022 - mdpi.com
… cell-penetrating siRNA delivery system … miRNA- and siRNa-based delivery systems
address some of the issues associated with miRNA- and siRNA-based cancer therapeutics…
被引用次数：28 相关文章 所有 16 个版本
[HTML] cell.comFull View

[HTML][HTML] siRNA versus miRNA as therapeutics for gene silencing

JKW Lam, MYT Chow, Y Zhang, SWS Leung - Molecular Therapy-Nucleic …, 2015 - cell.com
… siRNAs and miRNAs is … therapeutic approaches of siRNAs and miRNAs are therefore very
different. Hence, this review provides a comparison between therapeutic siRNAs and miRNAs …
被引用次数：1191 相关文章 所有 12 个版本
[HTML] nih.gov

Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer

T Ahmadzada, G Reid, DR McKenzie - Biophysical reviews, 2018 - Springer
… clinical practice for cancer treatment, three … in cancer development must be identified; (2)
an siRNA specific to the target gene must be designed and synthesized; (3) the synthetic siRNA …
被引用次数：201 相关文章 所有 7 个版本
[HTML] nih.gov

Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment

M Nishimura, EJ Jung, MY Shah, C Lu, R Spizzo… - Cancer discovery, 2013 - AACR
… gene silencing therapies for cancer and other diseases. … therapy by combining miRNA
and siRNA in nanoliposomal particles to target oncogenic pathways altered in ovarian cancer. …
被引用次数：181 相关文章 所有 10 个版本
[HTML] nih.gov

Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances

NS Gandhi, RK Tekade, MB Chougule - Journal of Controlled Release, 2014 - Elsevier
… This article is mainly focused on the siRNA and miRNA based delivery systems in the
treatment of cancers. The drug resistance mechanism is explained in detail elsewhere [72], [76]. …
被引用次数：402 相关文章 所有 9 个版本
[HTML] cell.comFull View

[HTML][HTML] Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy

Y Chen, X Zhu, X Zhang, B Liu, L Huang - Molecular therapy, 2010 - cell.com
… co-delivery of miRNA and siRNA as cancer therapeutic agents. The … therapeutic siRNAs or
miRNAs both in vitro and in animal models. Such results would contribute to the basic cancer …
被引用次数：664 相关文章 所有 11 个版本
[HTML] cell.com

[HTML][HTML] Therapeutic miRNA and siRNA: moving from bench to clinic as next generation medicine

C Chakraborty, AR Sharma, G Sharma… - Molecular Therapy …, 2017 - cell.com
… of therapeutic miRNAs and siRNAs. We present insights regarding significant siRNAs and
miRNAs in the therapeutic … CALAA-01 to inhibit tumor and cancer therapy M2 subunit of …
被引用次数：828 相关文章 所有 9 个版本
[HTML] nih.gov

Endosomolytic and tumor-penetrating mesoporous silica nanoparticles for siRNA/miRNA combination cancer therapy

Y Wang, Y Xie, KV Kilchrist, J Li… - … applied materials & …, 2020 - ACS Publications
… Systemic intravenous treatment of metastatic breast cancer with the … This work demonstrates
that siRNA-miRNA combination … a promising approach for metastatic cancer treatment. …
被引用次数：128 相关文章 所有 7 个版本

Efficient nanocarriers of siRNA therapeutics for cancer treatment

MA Subhan, VP Torchilin - Translational Research, 2019 - Elsevier
… MicroRNA (miRNA) and small interfering RNA (siRNA) represent 2 types of small RNA … are
21–23 nucleotides for siRNA and 18–25 nucleotides for miRNA. The basic difference is their …
被引用次数：150 相关文章 所有 6 个版本
[PDF] academia.edu

Delivering the promise of miRNA cancer therapeutics

DM Pereira, PM Rodrigues, PM Borralho… - Drug discovery today, 2013 - Elsevier
… small-molecule and siRNA therapeutics, to a novel … miRNA function and status in cancer,
miRNAs are generally classified as tumor suppressors or oncomiRs, with different therapeutic …
被引用次数：347 相关文章 所有 7 个版本