The emerging role of miRNAs in HTLV-1 infection and ATLL pathogenesis

R Moles, C Nicot - Viruses, 2015 - mdpi.com
MiRNAs might also induce gene silencing by interfering with protein translation [24]. … with
HTLV-1, however HTLV-1-encoded miRNAs have not been reported. Cellular miRNAs can …

Role of microRNAs in HTLV-1 infection and transformation

K Ruggero, A Corradin, P Zanovello, A Amadori… - Molecular aspects of …, 2010 - Elsevier
microRNA expression in HTLV-1-infected cell lines and ATLL cells, and the functional impact
of a subset microRNAs deregulated by HTLV-1 on cellular gene … may influence microRNA

MicroRNA miR-146a and further oncogenesis-related cellular microRNAs are dysregulated in HTLV-1-transformed T lymphocytes

K Pichler, G Schneider, R Grassmann - Retrovirology, 2008 - Springer
… , a single microRNA was downregulated and four microRNAs were overexpressed in
HTLV-/Tax-… Using online databases that catalogue predicted microRNA target genes we looked for …

Complex role of microRNAs in HTLV-1 infections

GC Sampey, R Van Duyne, R Currer, R Das… - Frontiers in …, 2012 - frontiersin.org
miRNAs in the life cycle and pathogenesis of HTLV-1 … elucidating HTLV-1 mediated
manipulation of host cell miRNA … , including the transcription of miRNA genes, is through the …

MicroRNA miR‐146a is induced by HTLV1 tax and increases the growth of HTLV1‐infected T‐cells

M Tomita, Y Tanaka, N Mori - International Journal of Cancer, 2012 - Wiley Online Library
… They are transcribed in primary miRNAs, which are long primary forms from miRNA genes
in the nucleus and transported into the cytoplasm after being processed into precursor …

Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus

MZ Ghobadi, E Afsaneh, R Emamzadeh… - BMC Medical …, 2023 - Springer
… However, we could only find one common miRNA and a few genes for each subtype. In this
study, we employed the weighted gene co-expression method for finding specific coding and …

Circulating miR-29c, miR-30c, miR-193a-5p and miR-885-5p: Novel potential biomarkers for HTLV-1 infection diagnosis

M Fayyad-Kazan, R ElDirani, E Hamade… - Infection, Genetics and …, 2019 - Elsevier
miRNAs profile in the serum of healthy and HTLV-1 infected individuals, our results revealed
several dysregulated miRNAsgene expression involves the gene of interest data (Ct gene

How HTLV-1 may subvert miRNAs for persistence and transformation

AB Bouzar, L Willems - Retrovirology, 2008 - Springer
HTLV-1 Tax directly transactivates cellular miRNA genes. Expression of a small non-coding
viral RNA by HTLV-1 could affect viral (C) or cellular (D) gene expression through …

HTLV-1 bZIP factor HBZ promotes cell proliferation and genetic instability by activating OncomiRs

C Vernin, M Thenoz, C Pinatel, A Gessain, O Gout… - Cancer research, 2014 - AACR
… expression accompany cell-associated replication of HTLV-1, we carried out miRNA
expression profiling of infected and uninfected CD4 + and CD8 + T cells derived from naturally …

MiR-150 in HTLV-1 infection and T-cell transformation

DM D'Agostino, V Raimondi, M Silic-Benussi… - Frontiers in …, 2022 - frontiersin.org
miRNA, miR-31, is silenced by geneticmiRNAs in normal naïve CD4+ T-cells (see below),
stands out among the many miRNAs that have been identified as deregulated by HTLV-1, as …