Understanding microRNA-mediated gene regulatory networks through mathematical modelling

X Lai, O Wolkenhauer, J Vera - Nucleic acids research, 2016 - academic.oup.com
… of network dynamics. Mathematical modelling can help dissecting the role of miRNAs in gene
regulatory networks, … into the function of miRNAs in the regulation of gene expression. Key …

MicroRNA-mediated regulatory circuits: outlook and perspectives

A Re, M Caselle, F Bussolino - Physical biology, 2017 - iopscience.iop.org
… Finally, to add perspective, we will introduce the role of long non-coding RNAs in the context
of the miRNA-mediated gene regulatory network, and discuss some evolutionary aspects of …

In silico model for miRNA-mediated regulatory network in cancer

KT Ahmed, J Sun, W Chen, I Martinez… - Briefings in …, 2021 - academic.oup.com
… is motivated by miRNA-mediated regulation of gene expression to … Next, a deep learning-based
fusion network model is … attributed to the miRNA-mediated regulation mechanism, which …

Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression

M Pu, J Chen, Z Tao, L Miao, X Qi, Y Wang… - Cellular and Molecular …, 2019 - Springer
… actions which form a regulatory network of a miRNA on its target are … of miRNA regulatory
network on target gene regulation and further highlight the potential application of the network

Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers

E Lee, K Ito, Y Zhao, EE Schadt, HY Irie, J Zhu - Bioinformatics, 2016 - academic.oup.com
… Our work provides a novel scheme to facilitate our understanding of miRNA. In summary,
inferred activity of key miRNA provided a functional link to its mediated regulatory network, and …

Identification of novel and salt-responsive miRNAs to explore miRNA-mediated regulatory network of salt stress response in radish (Raphanus sativus L.)

X Sun, L Xu, Y Wang, R Yu, X Zhu, X Luo, Y Gong… - BMC genomics, 2015 - Springer
… , salt-responsive miRNAs and their target genes in radish were comprehensively identified.
The results provide novel insight into complex miRNA-mediated regulatory network of salt …

Construction of microRNA-and microRNA*-mediated regulatory networks in plants

Y Meng, C Shao, L Gou, Y Jin, M Chen - RNA biology, 2011 - Taylor & Francis
… Finally, comprehensive miRNAand miRNA*-mediated regulatory networksnetworks for
biologists. This study could broaden the current understanding of miRNAmediated regulation in …

A network analysis of miRNA mediated gene regulation of rice: crosstalk among biological processes

C Mal, A Deb, M Aftabuddin, S Kundu - Molecular BioSystems, 2015 - pubs.rsc.org
… crops and miRNA regulation has … miRNA mediated gene regulatory network in roots, 16
vegetative and reproductive stage-specific regulation, 17 the genome-wide analysis of miRNA

A novel microRNA and transcription factor mediated regulatory network in schizophrenia

AY Guo, J Sun, P Jia, Z Zhao - BMC systems biology, 2010 - Springer
… our miRNA-mediated regulatory network analysis, we propose that EGRs, especially EGR3,
are key factors regulated … and miRNAs in signaling pathways and regulatory networks within …

Toward microRNA-mediated gene regulatory networks in plants

Y Meng, C Shao, M Chen - Briefings in bioinformatics, 2011 - academic.oup.com
… His current research centers on small RNA-mediated regulatory network construction and
… tools and data sources mentioned in this review for miRNA-mediated network construction …