… bind to NLRP3 that is translocated on mitochondria and activate the NLRP3 inflammasome.
… described mechanisms by which mitochondria regulate NLRP3 inflammasome activation. …

… result in a decrease in the mitochondrial fusion rate [115]. … with a decrease in mitochondrial
fusion and smaller mitochondria [116]. … PD, suggesting mitochondrial fusion deficiency [117]. …

… the full activation of NLRP3 inflammasome through the formation of the NLRP3-Mfn2-MAVS …
10 , suggesting that mitochondrial fusion is favorable to NLRP3 inflammasome assembly. In …

… outer membrane associated proteins that are crucial for mitochondrial fusion. Mice lacking
either mitofusin 1 or mitofusin 2 are embryonic lethal, demonstrating the critical roles played …

… of mitochondrial fusion, is required for the full activation of the NLRP3 inflammasome after
… Our results highlight the importance of mitochondria as a platform of NLRP3 inflammasome …

… deoxyribonucleic acid, and other mitochondria-associated proteins and lipids … the NLRP3
inflammasome. In addition, the processes of mitochondrial dynamics, such as fission and fusion…

… -1 cells showing increased mitochondrial fusion under these … remodeling of mitochondrial
morphology towards fusion in order … , called mitochondrial hyperfusion, prevents mitochondrial …

… that impaired mitochondrial dynamics affect NLRP3 inflammasome activation. … mitochondrial
fusion, reduced IL-1β secretion by RNA virus infection, suggesting that mitochondrial fusion …

… are required for mitochondrial fusion, activate the NLRP3 inflammasome in influenza and …
So far we have discussed how mitochondria play a crucial role in the NLRP3 inflammasome …

… Diverse stimuli have been shown to activate the NLRP3 inflammasome during infection
and … with mitochondrial destabilization may critically activate the NLRP3 inflammasome. …