Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

R Bravo, T Gutierrez, F Paredes, D Gatica… - The international journal …, 2012 - Elsevier
… The ER physically interacts with mitochondria. ► Calcium release from ER stores stimulates
mitochondrial bioenergetics as an adaptive response during the early phases of ER stress. …

[HTML][HTML] Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics

RJ Kaufman, JD Malhotra - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
endoplasmic reticulum (ER) serves as the primary calcium store in the metazoan cell, dynamic
calcium release to the cytosol, mitochondria… the ER to mitochondria plays a significant role …

[HTML][HTML] The unfolded protein response: at the intersection between endoplasmic reticulum function and mitochondrial bioenergetics

A Carreras-Sureda, P Pihán, C Hetz - Frontiers in Oncology, 2017 - frontiersin.org
Endoplasmic reticulum (ER) to mitochondria communication has emerged in recent
years … known as mitochondria-associated membranes (MAMs). At these domains, ER/mitochondria

[HTML][HTML] Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients …

G Leipnitz, AW Mohsen, A Karunanidhi, B Seminotti… - Scientific reports, 2018 - nature.com
… on mitochondrial bioenergetics and dynamics, respiratory chain (RC) and endoplasmic reticulum
(ER)-mitochondria … Fatty acid metabolism, basal and maximal respiration, mitochondrial

[HTML][HTML] … MOCS1 deficiencies: disruption of mitochondrial bioenergetics, dynamics, redox homeostasis and endoplasmic reticulum-mitochondria crosstalk in patient …

M Grings, B Seminotti, A Karunanidhi… - Scientific Reports, 2019 - nature.com
… their response to a novel mitochondrial antioxidant. After confirming … of mitochondrial
bioenergetics and homeostasis. All of the patient fibroblasts demonstrated decreased mitochondrial

[HTML][HTML] Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy

A Filipe, A Chernorudskiy, S Arbogast… - Cell Death & …, 2021 - nature.com
… between mitochondrial bioenergetics and SR homeostasis in skeletal muscle, identify a
systemic metabolic/bioenergetic component in SEPN1-RM and suggest mitochondria as a novel …

[HTML][HTML] Endoplasmic reticulum stress disrupts mitochondrial bioenergetics, dynamics and causes corneal endothelial cell apoptosis

S Qureshi, S Lee, W Steidl, L Ritzer… - … & Visual Science, 2023 - jov.arvojournals.org
… disruption of mitochondrial pathways and their role in CEnC apoptosis. We hypothesize
that ER stress disrupts mitochondrial bioenergetics, dynamics and activates mitochondrial-…

Dieldrin-induced neurotoxicity involves impaired mitochondrial bioenergetics and an endoplasmic reticulum stress response in rat dopaminergic cells

JT Schmidt, A Rushin, J Boyda, CL Souders II… - Neurotoxicology, 2017 - Elsevier
Mitochondria are sensitive targets of … As mitochondrial dysfunction is involved in the etiology
of PD, this study aimed to determine whether DLD impaired mitochondrial bioenergetics in …

Calcium and bioenergetics: from endoplasmic reticulum to mitochondria

D Lee, M Michalak - Animal cells and systems, 2012 - Taylor & Francis
… to bioenergetic stress even in the presence of nutrients. Conversely, a constitutive low level
of InsP 3 R-mediated Ca 2+ transfer to mitochondria … optimal mitochondria bioenergetics by …

Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

R Bravo, JM Vicencio, V Parra… - Journal of cell …, 2011 - journals.biologists.com
… Increasing evidence indicates that endoplasmic reticulum (ER) stress activates the adaptive
unfolded protein response (UPR), but that beyond a certain degree of ER damage, this …