… 1), consistent with its role in mitochondrial biogenesis in normal metabolic adaptation or in
… Mitochondrial biogenesis is increased after cerebral hypoxia 21 and ischemia. Oxygen and …

… Key causes of AKI include sepsis, ischemia-reperfusion injury (IRI) and … in mitochondrial
biogenesis, its role in health and disease, and the involvement of mitochondria in kidney disease…

… AKI following cisplatin treatment or renal ischemiareperfusion injury, whereas drugs …
Mitochondrial biogenesis requires coordinated signaling between the nuclear and mitochondrial …

… To evaluate the energy deficit corollary of renal ischemia, we determined renal tissue ATP
levels. At 24 hr of reperfusion, the vehicle group showed a 48% decrease in ATP levels as …

… that conduct antioxidant defense and mitochondrial biogenesis, respectively. … renal I/R
injury in nondiabetic rats in this study by promoting autophagy and mitochondrial biogenesis …

… of mitochondrial ROS and … mitochondrial biogenesis and suppressed mitophagy. Expression
of PPAR‐γ coactivator 1α (PGC‐1α), a master regulator of mitochondrial biogenesis, was …

… In response, mitochondrial biogenesis (MB) occurs to maintain cellular homeostasis against
… new mitochondria [12]. Taken together, the ability of maintaining mitochondrial homeostasis …

… autophagosome formation, mitochondrial biogenesis, and … and mitochondrial biogenesis,
which protected the kidney against … acute kidney injury (aki) is one of the major causes of renal …

… We suggest that mitochondrial biogenesis following oxidant injury is mediated by p38 and
EGFR … Ischemia-reperfusion injury in the kidney and other organs is characterized by de-…

… the kidney cortex. Moreover, TILLIR reduced mRNA levels of a master regulator of mitochondrial
biogenesis PGC-1α, and its downstream genes NDUFS1 and ATP5o in the renal cortex. …