Role of mitochondrial dysfunction in cancer progression

CC Hsu, LM Tseng, HC Lee - Experimental Biology and …, 2016 - journals.sagepub.com
… tumor suppressor p53 regulate mitochondrial respiration and cellular metabolism by …
mitochondrial dysfunction plays a critical role in cancer progression and that targeting mitochondrial

Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression

J Ježek, KF Cooper, R Strich - Antioxidants, 2018 - mdpi.com
mitochondrial network is linked with several physiological indicators of mitochondrial dysfunction,
including loss of mitochondrial … glycolysis, and increased mitochondrial ROS formation […

Mitochondrial dysfunction in cancer

ML Boland, AH Chourasia, KF Macleod - Frontiers in oncology, 2013 - frontiersin.org
… in cancer has knock on effects for cell proliferation and growth. We define major forms of
mitochondrial dysfunction … genome mutations actually drive tumor growth and progression, as …

The significance of mitochondrial dysfunction in cancer

Y Luo, J Ma, W Lu - International journal of molecular sciences, 2020 - mdpi.com
… in tumorigenesis and malignant progression, the battle to determine whether an mtDNA
mutation is a driver mutation for cancer initiation and progression or merely a passenger …

[HTML][HTML] Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection

S Srinivasan, M Guha, A Kashina… - Biochimica et Biophysica …, 2017 - Elsevier
… in early stages of tumor initiation and progression observed in our and others' studies are
likely to be different from that reported in tumor metastasis and drug resistance [150] where …

Mitochondrial dysfunction in cancer

K Księżakowska-Łakoma, M Żyła… - Menopause Review …, 2014 - termedia.pl
… their potential role in endometrial cancer progression and indicate an increase of mitochondrial
biogenesis in this cancer. Guerra et al. investigated 23 type I endometrial cancer (EC) …

Mitochondrial dysfunction at the center of cancer therapy

HY Chiu, EXY Tay, DST Ong… - Antioxidants & redox …, 2020 - liebertpub.com
… types of mitochondrial dysfunctions in cancer. Through … mitochondria dysfunctions in cancer
progression that have led to the development of therapeutic options. Current mitochondrial

[HTML][HTML] Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression

HC Lee, KH Huang, TS Yeh, CW Chi - World Journal of …, 2014 - ncbi.nlm.nih.gov
… by mitochondrial dysfunction may be involved in the malignant changes of gastric cancer. …
mutation and mitochondrial dysfunction affect gastric cancer progression remains unclear. …

Mitochondrial dysfunction: a novel potential driver of epithelial-to-mesenchymal transition in cancer

F Guerra, N Guaragnella, AA Arbini, C Bucci… - Frontiers in …, 2017 - frontiersin.org
… Type III EMT is associated with cancer progression (18) and is the focus of this review. …
promoting mitochondrial dysfunction that has been implicated in EMT induction in cancer cells. …

[HTML][HTML] Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma

CC Hsu, HC Lee, YH Wei - World journal of gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
… and mitochondrial dysfunction in the progression and … in cancer progression, including
angiogenesis, invasion and metastasis[55]. These findings suggest that mitochondrial dysfunction