… storage of iron within this organelle. In this review, we discuss the role of mitochondrial iron
pathways in human health and disease. We focus on the role of mitochondrial iron pathways …

… of iron to the mitochondria and normal mitochondrial iron metabolism, including heme
synthesis and iron-sulfur cluster biogenesis. Much of our understanding of mitochondrial iron …

… overload promotes ROS production during mitochondrial electron … of iron homeostasis,
mitochondrial iron metabolism, and how mitochondrial iron imbalances-induced mitochondrial …

… mitochondrial biology and discuss human diseases associated with aberrations in … a
mitochondrial iron exporter because decreased expression leads to mitochondrial iron accumulation…

… metabolism and bioavailability, and our current understanding of human iron requirement …
Internalized iron is transported to mitochondria for the synthesis of heme or iron-sulfur clusters, …

… human myocardium, its determinants, and about the consequences for myocardial mitochondrial
… , we sought to examine myocardial iron content and mitochondrial function directly in a …

… Before addressing recent findings in the metabolism of mitochondrial iron, we will first briefly
describe the relatively well-characterized molecular pathways of cellular iron metabolism …

… mitochondrial iron trafficking need to be identified. A growing list of rare human diseases
manifest severe mitochondrial iron … the proteins involved in mitochondrial iron homeostasis [25]. …

… The effects of iron deficiency and mild iron excess on mitochondrial function and oxidative
… high iron either given daily or every 3 days are equally effective in correcting iron deficiency, …

… is stored and trafficked through the body, intracellularly, and within mitochondria via …
involved in mitochondrial iron trafficking and storage, as well as mitochondrial iron–sulfur cluster …