Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
… how mitochondria generate and regulate the production of mtROS and the function of mtROS
both in physiological and pathological conditions. … inflammatory diseases and inflammatory …
both in physiological and pathological conditions. … inflammatory diseases and inflammatory …
Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies
… in the coordination of pro-inflammatory signaling from the … In this regard, mitochondrial
reactive oxygen species are emerging … by mitochondrial mechanisms, including reactive oxygen …
reactive oxygen species are emerging … by mitochondrial mechanisms, including reactive oxygen …
Reactive oxygen species in metabolic and inflammatory signaling
… Mitochondrial reactive oxygen species (ROS) production. MitoROS are produced as a normal
by-product of mitochondrial respiration and metabolic enzymatic activity. Under settings of …
by-product of mitochondrial respiration and metabolic enzymatic activity. Under settings of …
[PDF][PDF] Physiological roles of mitochondrial reactive oxygen species
LA Sena, NS Chandel - Molecular cell, 2012 - cell.com
… Historically, mitochondrial reactive oxygen species (mROS) were thought to exclusively
cause cellular damage and lack a physiological function. Accumulation of ROS and oxidative …
cause cellular damage and lack a physiological function. Accumulation of ROS and oxidative …
[HTML][HTML] Mitochondrial reactive oxygen species are essential for the development of psoriatic inflammation
S Mizuguchi, K Gotoh, Y Nakashima… - Frontiers in …, 2021 - frontiersin.org
… inflammation. … mitochondrial reactive oxygen species (mtROS) after IMQ stimulation. Because
the inhibition of mtROS suppressed IMQ-induced DC activation and psoriatic inflammation, …
the inhibition of mtROS suppressed IMQ-induced DC activation and psoriatic inflammation, …
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
AC Bulua, A Simon, R Maddipati, M Pelletier… - Journal of Experimental …, 2011 - rupress.org
… mitochondrial ROS as a driver of inflammation in TRAPS and potentially other autoinflammatory
diseases… role for mitochondrial ROS in the induction of inflammatory cytokines upstream …
diseases… role for mitochondrial ROS in the induction of inflammatory cytokines upstream …
Mitochondrial DNA and inflammatory diseases
… accompanied by mitochondrial dysfunction, which is directly involved in the cell death.
Recently, a direct implication of mitochondrial reactive oxygen species and, particularly, mtDNA in …
Recently, a direct implication of mitochondrial reactive oxygen species and, particularly, mtDNA in …
Mitochondrial reactive oxygen species in physiology and disease
S Antonucci, F Di Lisa, N Kaludercic - Cell Calcium, 2021 - Elsevier
… Mitochondrial reactive oxygen species (mROS) are routinely produced at several sites
within the organelle. The balance in their formation and elimination is maintained by a complex …
within the organelle. The balance in their formation and elimination is maintained by a complex …
Mitochondrial reactive oxygen species and risk of atherosclerosis
M Hulsmans, E Van Dooren, P Holvoet - Current atherosclerosis reports, 2012 - Springer
… Mechanisms that lead to increased mitochondrial reactive oxygen species (mtROS) production.
Because the overall mtROS levels are determined by the rates of ROS generation and …
Because the overall mtROS levels are determined by the rates of ROS generation and …
Mitochondrial redox signaling: interaction of mitochondrial reactive oxygen species with other sources of oxidative stress
… Mitochondrial reactive oxygen species and calcium uptake regulate activation of phagocytic
NADPH oxidase. Am J Physiol Regul Integr Comp Physiol 302: R1134–R1142, 2012. 36. …
NADPH oxidase. Am J Physiol Regul Integr Comp Physiol 302: R1134–R1142, 2012. 36. …
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