… Mitochondria are inevitable sources for the generation of mitochondrial reactive oxygen
species … of mtROS with mitochondrial damage leads to sustained inflammation, resulting in …

… Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases
and … The role of mitochondria in reactive oxygen species generation and its implications for …

… of superoxide from mitochondria as a unifying theory to … the production of distinct reactive
oxygen species (ROS) in vivo, … pathways and represent normal mitochondrial function. This …

… Mitochondrial reactive oxygen species are mainly produced at the electron transport chain
(ETC) during the oxidative phosphorylation process, during which molecular oxygen (O 2 ) is …

… in accumulation of damaged mitochondria, increased mitochondrial ROS, and activation
of … may sense mitochondrial damage and dysfunction in inflammatory diseases (Zhou et al., …

… granulomatous disease (CGD… reactive oxygen species (ROS) via this enzyme system.
Patients with CGD are highly susceptible to infections and often suffer from inflammatory disorders; …

… but also a crucial contributor to tubulointerstitial inflammation … activation by mitochondrial
reactive oxygen species (mROS). … , renal infiltration of inflammatory cells, tubular dilation and …

… of mitochondrial dysfunction in neurodegenerative diseases. Here, we summarize the existing
knowledge of the mitochondrial function in reactive oxygen species generation … diseases. …

… Mitochondrial reactive oxygen species (mtROS) have been proposed to regulate the activation
of the inflammatory … by treatment with a mitochondrial-targeted exogenous antioxidant (…

… the pro-inflammatory cytokine interleukin-1β (pro-IL-1β) into … active form (IL-1β) and promotes
inflammation. NLRP3 inflammasome stimuli induce mitochondrial reactive oxygen species (…