[HTML][HTML] Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases
… Of interest, mitochondria-derived reactive oxygen species (mtROS) is a further key mediator
in this process. Pharmacologic induction of mtROS correlates with higher secretion of active …
in this process. Pharmacologic induction of mtROS correlates with higher secretion of active …
Role of mitochondrial reactive oxygen species in homeostasis regulation
B Zhang, C Pan, C Feng, C Yan, Y Yu, Z Chen… - Redox …, 2022 - Taylor & Francis
… Mitochondria are the main source of reactive oxygen species (ROS) in cells. Early studies
have shown that mitochondrial reactive oxygen species … outcomes of many diseases, and are …
have shown that mitochondrial reactive oxygen species … outcomes of many diseases, and are …
Role of mitochondrial reactive oxygen species in the activation of cellular signals, molecules, and function
HP Indo, CL Hawkins, I Nakanishi, K Matsumoto… - … of Mitochondria, 2017 - Springer
… Mitochondria are a major source of intracellular energy and reactive oxygen species in
cells… Here, we review evidence of signal transduction control by mitochondrial superoxide …
cells… Here, we review evidence of signal transduction control by mitochondrial superoxide …
Peroxyauraptenol inhibits inflammation and NLRP3 inflammasome activation by inhibiting reactive oxygen species generation and preserving mitochondrial integrity
LK Chao, CH Lin, HW Chiu, WT Wong… - Journal of agricultural …, 2015 - ACS Publications
… inflammatory activity by reducing reactive oxygen species generation (including mitochondrial…
C-α/δ phosphorylation, and the release of mitochondrial DNA into the cytosol. In addition, …
C-α/δ phosphorylation, and the release of mitochondrial DNA into the cytosol. In addition, …
Reactive oxygen species and superoxide dismutases: role in joint diseases
V Afonso, R Champy, D Mitrovic, P Collin, A Lomri - Joint bone spine, 2007 - Elsevier
… TNF-α overproduction in inflammatory conditions is associated … 2 radical dot − and its
derivatives in inflammatory conditions. … SOD2 is found in mitochondria and provides vital …
derivatives in inflammatory conditions. … SOD2 is found in mitochondria and provides vital …
Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases
CSD Cruz, MJ Kang - Mitochondrion, 2018 - Elsevier
… Mitochondrial dysfunction or damage causes the following individually or simultaneously:
mitochondrial reactive oxygen species (mtROS), aberrant calcium mobilization, reduction in …
mitochondrial reactive oxygen species (mtROS), aberrant calcium mobilization, reduction in …
Mitochondrial reactive oxygen species in cell death signaling
C Fleury, B Mignotte, JL Vayssière - Biochimie, 2002 - Elsevier
… Apart from this pivotal role of mitochondria during the execution phase of apoptosis (… ), it
appears that reactive oxygen species (ROS) produced by the mitochondria can be involved in …
appears that reactive oxygen species (ROS) produced by the mitochondria can be involved in …
NADPH oxidase-and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?
EA Bordt, BM Polster - Free Radical Biology and Medicine, 2014 - Elsevier
… understood, yet reactive oxygen species are increasingly … highlight studies linking reactive
oxygen species, in particular … a specific role for mitochondrial reactive oxygen species in the …
oxygen species, in particular … a specific role for mitochondrial reactive oxygen species in the …
Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1α in long-lived Mclk1+/− mouse mutants
… Mitochondrial reactive oxygen species (ROS) are believed to … Mclk1 encodes a mitochondrial
protein that is necessary for … -lived despite increased mitochondrial ROS and decreased …
protein that is necessary for … -lived despite increased mitochondrial ROS and decreased …
Reactive oxygen species in macrophages: sources and targets
M Canton, R Sánchez-Rodríguez, I Spera… - Frontiers in …, 2021 - frontiersin.org
… Our studies support the relevance of targeting the mitochondrial enzyme MAO to counteract
inflammatory diseases for several reasons. Indeed, MAO inhibitors, for which the mechanism …
inflammatory diseases for several reasons. Indeed, MAO inhibitors, for which the mechanism …